arXiv Machine Learning

A Zero-Shot Deep Image Prior Framework for Denoising and Deconvolution in Fluorescence Microscopy

arXiv:2606. 28431v1 Announce Type: cross Abstract: Fluorescence microscopy images are degraded by noise and diffraction-induced blur, which compromise structural fidelity and limit quantitative analysis.

arXiv AI
Jul 28

scMIR: a vision-language foundation model for single-cell light microscopy image representation

arXiv:2607. 22712v1 Announce Type: cross Abstract: Single-cell light microscopy images have become an important data source for characterizing cell phenotypes, but their complexity and heterogeneity pose challenges to high-throughput automated analysis.

By Yifan Shang (Department of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong, China, College of Computer Science and Electronic Engineering, Hunan University, Changsha, China), Jiahui Tan (College of Computer Science and Electronic Engineering, Hunan University, Changsha, China), Xiangxiang Zeng (College of Computer Science and Electronic Engineering, Hunan University, Changsha, China), Renjie Zhou (Department of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong, China)
Hugging Face Trending Papers
Jun 30

MG-SpaIR: Multi-grade Sparse-guided Implicit Representation for Training-Data-Free Image Restoration

MG-SpaIR is a training-data-free framework for restoring a clean image from a single observation corrupted by a mixture of blur, downsampling, noise, and missing pixels. Building on implicit neural representations (INRs), we introduce a multi-grade coarse-to-fine residual hierarchy that progressively refines the reconstruction across resolution grades, improving representational fidelity and mitigating spectral limitations.

arXiv AI
Aug 18

CG-GLORE: A Conjugate Gradient-Based Global-Local Regularization Network for Sparse-View CT Reconstruction

arXiv:2608. 15246v1 Announce Type: cross Abstract: Sparse-view computed tomography (CT) reduces radiation dose by acquiring fewer projection views, but the resulting inverse problem is highly ill-posed and often produces severe streak artifacts.

By Tran Xuan Hieu Le, Doanh C. Bui, Vu Trung Duong Le, Hoai Luan Pham, Khang Nguyen, Mai K. Nguyen, Tu Bao Ho, Yasuhiko Nakashima
arXiv AI
Jul 31

PatchDenoiser: Parameter-efficient multi-scale patch learning and fusion denoiser for Low-dose CT imaging

arXiv:2602. 21987v3 Announce Type: replace-cross Abstract: Low-dose CT images are essential for reducing radiation exposure in cancer screening, pediatric imaging, and longitudinal monitoring protocols, but their quality is often degraded by noise from low-dose acquisition, patient motion, or scanner limitations, affecting both clinical interpretation and downstream analysis.

By Jitindra Fartiyal, Pedro Freire, Sergei K. Turitsyn, Sergei G. Solovski
arXiv Machine Learning
Oct 19

Learning the Shared Latent Structure of Cryo-EM Inverse Problems

The paper introduces EMber, a family of vision transformers trained on over 50 million cryo‑EM particle images and simulated projections, to learn a shared latent representation for multiple inverse problems in cryo‑EM. By employing self‑distillation with global and masked patch objectives, EMber captures spatially localized structural differences and improves performance on conformational and compositional discrimination by roughly 15 percentage points compared to existing methods. The authors demonstrate that these representations enable accurate estimation of conformational populations and yield high‑quality reconstructions in fewer training epochs.

By Nithin Chalapathi, Theo Sternlieb, Ethan Han, Sonya M. Hanson, Pilar Cossio, Aditi S. Krishnapriyan, Ritwik Gupta