AI safety and alignment

Alignment, interpretability, red-teaming, bias and privacy: the research on what these systems do when they misbehave.

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arXiv AI
Oct 7

Cylindrical Geodesic Flow Matching for Quasiperiodic Physiological Signal Transformation

The paper introduces cylindrical geodesic flow matching, a method for translating quasiperiodic cardiovascular waveforms between different body locations. By replacing the standard affine path in flow matching with a closed‑form geodesic on a phase–amplitude cylinder, the approach preserves amplitude and instantaneous frequency during interpolation. Experiments on photoplethysmography and seismocardiography data show that this geometry‑aware method outperforms interpolation baselines and matches or exceeds supervised models, reducing error metrics by up to ~15%.

By Onur Selim Kilic, Afra Nawar, Cem Okan Yaldiz, Michael J. Cho, Ahmet Rasim Emirdagi, Demet Tangolar, Amirali Aghazadeh, Amit J. Shah, Omer T. Inan
arXiv AI
Oct 7

CausalBind: Causal Modeling and Learning for Protein-Molecule Virtual Screening

CausalBind introduces a causal modeling framework for protein‑molecule virtual screening that focuses on sparse cross‑modality interactions rather than dense holistic alignment. By formalizing a V‑structure causal model with Heckman‑style selection, the authors prove that latent interaction concepts are identifiable only under sparsity constraints and propose three implementation variants. Experiments on DUD‑E and LIT‑PCBA benchmarks demonstrate that all variants outperform strong retrieval baselines, especially in early enrichment and out‑of‑distribution generalization.

By Loka Li, Jin Tian, Kun Zhang
arXiv AI
Oct 7

Local2Mesh: Spatially Localized Contour-to-Mesh for Left Ventricular Reconstruction from Sparse 2D Cardiac MRI

Local2Mesh is a spatially localized contour‑to‑mesh framework that reconstructs 3‑D left ventricular geometry from sparse 2‑D cardiac MRI contours without requiring 3‑D mesh annotations. It corrects inter‑slice misalignment through geometry‑aware alignment and routes contour features to template vertices via a plane‑aware Local Router, then jointly uses local and global features to deform a template mesh. Experiments on M&Ms‑2 and ACDC datasets show superior geometric reconstruction, functional estimation, and disease classification compared to existing methods, with strong cross‑dataset generalization.

By Haoyu Wu, Ling Lin, Pascal Lef\`evre, Ruizhe Li, Xiaowu Sun
arXiv Machine Learning
Oct 7

Learning from Unreliable Trajectories: Adversarially-Robust Federated Q-Learning

The paper introduces Robust Async-Fed-Q, an epoch‑based federated Q‑learning algorithm that combines variance‑reduced Bellman operator estimation with robust server aggregation. It provides high‑probability finite‑time guarantees showing that honest agents retain sample‑efficiency benefits even when some agents act adversarially, with the adversarial impact diminishing as honest data grows. The authors also present matching lower bounds, extend the framework to single‑trajectory sampling and heterogeneous coverage, and improve communication complexity for asynchronous federated Q‑learning.

By Sreejeet Maity, Aritra Mitra