Semantic-Anchored Evidential Fusion for Domain-Robust Whole-Slide Survival Analysis
arXiv:2606. 19966v1 Announce Type: cross Abstract: Whole-slide images (WSIs) are widely used for computational cancer prognosis.
arXiv:2510. 00053v2 Announce Type: replace-cross Abstract: Pathology whole-slide images (WSIs) are widely used for cancer survival analysis because of their comprehensive histopathological information at both cellular and tissue levels, enabling quantitative, large-scale, and prognostically rich tumor feature analysis.
arXiv:2606. 19966v1 Announce Type: cross Abstract: Whole-slide images (WSIs) are widely used for computational cancer prognosis.
arXiv:2510.06113v2 Announce Type: replace Abstract: Survival analysis plays a vital role in making clinical decisions. However, the models currently in use are often difficult to interpret, which red...
The paper introduces the Evidential Missing Modality Survival Fusion (EMMS) model, which predicts survival outcomes using multimodal data even when some modalities are missing. EMMS applies Dempster‑Shafer theory and Gaussian Random Fuzzy Numbers to fuse information, accounting for both aleatoric and epistemic uncertainty and the reliability of each modality. Experiments on four cancer datasets show that EMMS achieves state‑of‑the‑art performance while providing calibrated, interpretable uncertainty estimates without extra computational cost.
arXiv:2609.00396v1 Announce Type: new Abstract: Histopathological whole slide images (WSIs) are central to cancer diagnosis, but their gigapixel scale, tissue heterogeneity, weak slide-level supervis...
The paper introduces CoPath, a lightweight framework for diagnosing peripheral neuroblastic tumors (pNTs) from whole-slide images. CoPath combines CoHisNet, a multi‑scale feature‑fusion network that replaces traditional MLPs with Kolmogorov‑Arnold Network layers for efficient nonlinear modeling, and PathVote, which aggregates patch‑level predictions using pathology‑informed priors. Experiments on a private pNT cohort and the public BreakHis dataset show that CoPath matches or surpasses existing classifiers while reducing computational complexity.
Survival analysis on Whole Slide Images (WSIs) is important in computational pathology for prognosis estimation and treatment planning. However, existing survival models are typically trained independently for each cancer cohort, making continual adaptation computationally expensive for gigapixel-scale WSIs.
The paper introduces a pipeline that uses publicly available whole slide image foundation models (FMs) to automatically triage slides by ranking them based on zero‑shot classification predictions. This approach accurately identifies slides containing the most tumor, achieving top‑2 ranking for patients with up to 43 slides across multiple datasets. The study also proposes a ranked evaluation framework to benchmark FM performance in slide triage.
PathoHR is a new pipeline for predicting breast cancer survival from high‑resolution pathological images. It uses a plug‑and‑play Vision Transformer to enhance patch‑wise whole slide image representations, evaluates multiple similarity metrics to optimize feature learning, and shows that smaller, enhanced patches can match or surpass the accuracy of larger raw patches while cutting computational cost. The authors provide experimental evidence that this approach improves both accuracy and efficiency in computational pathology.
arXiv:2607. 20742v1 Announce Type: new Abstract: Multimodal learning is a robust approach to improve predictive performance in applications such as medical prognosis.
arXiv:2606. 17115v1 Announce Type: cross Abstract: Foundation models (FMs) have emerged as powerful representation extractors for medical data, yet their generalizability to datasets under distribution shift remains underexplored.
arXiv:2606. 06983v1 Announce Type: cross Abstract: Computational pathology requires visual representations that transfer across diverse clinical endpoints and remain robust to variation in magnification, staining, scanner type, slide preparation, and input resolution.
MIST is a multimodal survival prediction framework that fuses whole-slide images and genomic profiles by representing genomic features as tokens that query histology context tokens derived from a foundation model. The architecture enriches molecular information with histology context before survival prediction, avoiding late-stage merging of separately encoded modalities. Training incorporates discrete-time survival prediction, genomic feature masking, WSI dropout, and contrastive alignment, and demonstrates improved external C-index across colon, renal, lung, and glioblastoma cohorts compared to standard fusion baselines.