arXiv Computer Vision By Mohamed Azzam, Ruobing Liu, Esther C. Ugwueke, Ziyang Xu, Shibiao Wan, Alex Foy, Abraham Zabih, Jason Christensen, Neil Hamill, Ling Li, Jieqiong Wang

Towards Whole-Study Screening for Congenital Heart Disease in Fetal Ultrasound Using Multiple Instance Learning

Read the original on arXiv Computer Vision →

The paper presents a two‑stage framework for prenatal congenital heart disease (CHD) screening that operates directly on whole fetal ultrasound studies. It first learns transferable frame representations via self‑supervised masked‑autoencoder pre‑training, then identifies cardiac frames with a disease‑robust module and aggregates them using a transformer‑based multiple instance learning model to produce a case‑level diagnosis. The approach achieves high performance (AUC 0.985, specificity 0.990) on an internal test set and, after label‑free CORAL adaptation, improves to an AUC of 0.944 on an external cohort, outperforming existing baselines.

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