arXiv Machine Learning By Jingyao Zhang, Yuxuan Li, Lu Han, Ali Anaissi, Nguyen H. Tran

Rethinking the Information Bottleneck: Structured Decomposition under Label-Induced Partitions

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The paper proposes a structured version of the Information Bottleneck (IB) that separates label-relevant structure from within-condition variation using a dual-bottleneck formulation. It introduces a conditional KL term that targets within-condition information, allowing explicit control over nuisance-like variation in learned representations. Experiments demonstrate improved performance in low-data classification and consistent gains on dense prediction tasks.

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arXiv Computer Vision
Sep 3

Synergistic Information Disentanglement for Omni-modal Slide Representation Learning in Computational Pathology

The paper introduces Φ-Omni, a self‑supervised learning framework for computational pathology that disentangles synergistic information across histology, genomics, and clinical reports using Partial Information Decomposition. By employing a Synergistic Information Bottleneck and a ΦID objective, the method suppresses redundant signals while maximizing irreducible cross‑modal synergy, leading to improved few‑shot performance on breast and lung whole‑slide image datasets. The authors demonstrate that Φ-Omni outperforms both supervised and other SSL baselines on eight external tasks.

By Mingxin Liu, Chengfei Cai, Anwen Lu, Pengbo Xu, Jun Li, Jinze Li, Depin Chen, Jun Xu