Privacy-Preserving Detection of Rare Disease-Associated Cell Subsets via Secure Multi-Party Computation
Read the original on arXiv Machine Learning →The Flow has not summarised this story yet — read it at arXiv Machine Learning.
The Flow has not summarised this story yet — read it at arXiv Machine Learning.
GRIN+ is a new machine unlearning framework that targets fast and precise data erasure in imbalanced medical datasets. It separates unlearning‑specific knowledge from general representations by analyzing gradient contributions of forget and retain sets, introduces a class‑adaptive influence scoring to counter gradient dominance, and uses a direction‑constrained update to protect essential clinical knowledge. Benchmarks on skin cancer, brain tumor, and breast ultrasound data show that GRIN+ balances privacy, efficiency, and utility, achieving high diagnostic accuracy and faster runtime than existing methods.
Efficient Provably Private Classification with a Tabular Foundation Model introduces PrivTab, a tabular foundation model that embeds differential privacy directly into its architecture. Pretrained on simulated datasets, PrivTab uses in-context learning to convert sensitive rows into compact, provably private summaries, enabling a single forward pass for classification. The model outperforms private linear and neural‑network baselines under moderate-to-strong privacy, shows negligible membership leakage, maintains well‑calibrated predictions, and reduces dataset fitting time by 10,000×.
The paper demonstrates that publicly available clinical machine learning models, such as logistic regression (LR), pose significant privacy risks because attackers can recover model parameters and identify training cohorts through various membership inference attacks. The authors show that even small cohorts can be reliably identified and that common practices like cross-validation can worsen the risk. To mitigate this, they propose a quantum-inspired defense that tensorizes discretized models into tensor trains (TTs), which obfuscates parameters, preserves accuracy, and maintains interpretability while providing black‑box protection comparable to Differential Privacy.
arXiv:2607. 19400v1 Announce Type: new Abstract: Pre-trained foundation models (FMs) have begun transforming single-cell genomics, but scaling them raises privacy concerns.
Privacy-sensitive and distributed characteristics of multi-center medical data bring severe obstacles to centralized modeling for accurate early prediction of sepsis. Federated learning (FL) has attracted growing attention as a promising framework for collaborative model development, as it allows multiple institutions to jointly train predictive models without directly sharing or centralizing raw data.
arXiv:2608. 13773v1 Announce Type: cross Abstract: Neural networks are increasingly deployed in high-stakes applications with growing privacy leakage concerns.