arXiv Machine Learning

Predictive single cell foundation model for gene regulation and aging with privacy-preserving tabular learning

arXiv:2607. 19400v1 Announce Type: new Abstract: Pre-trained foundation models (FMs) have begun transforming single-cell genomics, but scaling them raises privacy concerns.

arXiv AI
Jul 23

SynPre-FL: Synthetic data-driven pretraining integrated Federated Learning training framework

arXiv:2607. 19524v1 Announce Type: cross Abstract: Federated learning (FL) offers a promising approach to privacy-preserving clinical risk prediction, but its deployment remains limited by restricted data sharing, client heterogeneity, class imbalance, and the lack of realistic tabular electronic health record (EHR) benchmarks.

By Akarsh K Nair, Muhammad Arifur Rahman, Nicholas Shopland, Andy Burton, Jun He, Yuan Shen, David Baldwin, Emma O'Dowd, Amna Burzic, Mufti Mahmud, David J. Brown
arXiv Machine Learning
Jul 7

Batch effects can impair federated learning in multi-center omics studies

arXiv:2412. 05894v2 Announce Type: replace-cross Abstract: Federated learning (FL) enables collaborative analysis of biomedical data without exchanging sensitive patient-level information, but its performance in multi-center studies may be compromised by batch effects which can obscure biological signals.

By Yuliya Burankova, Julian Klemm, Jens J. G. Lohmann, Anne Hartebrodt, Ahmad Taheri, Niklas Probul, Jan Baumbach, Olga Zolotareva
Hugging Face Trending Papers
Jun 3

Federated Learning for Multi-Center Sepsis Early Prediction with Privacy-Preserving

Privacy-sensitive and distributed characteristics of multi-center medical data bring severe obstacles to centralized modeling for accurate early prediction of sepsis. Federated learning (FL) has attracted growing attention as a promising framework for collaborative model development, as it allows multiple institutions to jointly train predictive models without directly sharing or centralizing raw data.

arXiv Machine Learning
Jun 9

Integrating gene regulatory priors into Transformer attention with scTransformer for interpretable scRNA-seq analysis

arXiv:2606. 09558v1 Announce Type: cross Abstract: Motivation: Transformer-based models are increasingly applied to large-scale single-cell transcriptomics, showing strong performance through self-supervised learning on millions of cells.

By Mikele Milia, Louis Fabrice Tshimanga, Henning Mueller, Manfredo Atzori, Barbara Di Camillo
arXiv AI
Jun 18

PSyGenTAB: A Privacy-Preserving Framework for Synthetic Clinical Tabular Data Generation via Constrained Optimization

arXiv:2606. 18518v1 Announce Type: cross Abstract: The development of medical AI is constrained by limited access to high-quality clinical data due to institutional silos and strict privacy regulations such as HIPAA and GDPR.

By Arshia Ilaty, Hossein Shirazi, Manasi Chitale, Kedar Hegde, Dhanalakshmi Ramesh, Rashmi S. Manjunath, Amir Rahmani, Hajar Homayouni
arXiv AI
Jul 23

Trustworthy Privacy-Preserving Multimodal Federated Learning for Personalised Breast Cancer Prediction

arXiv:2607. 19532v1 Announce Type: cross Abstract: Federated learning has emerged as a potential solution to privacy concerns associated with using sensitive health data for training predictive models, particularly in personalised cancer care.

By Ruth Amey, Muhammad Arifur Rahman, Taha Osman, Nicholas Shopland, Andy Burton, Mufti Mahmud, David J. Brown
arXiv Machine Learning
Jun 24

Federated Survival Analysis in Healthcare: A Multi-Model Evaluation on Cross-Institutional Heterogeneous Breast Cancer Data

arXiv:2606. 23871v1 Announce Type: new Abstract: Survival analysis is central to clinical decision-making, yet reliable time-to-event models require large, diverse cohorts that are rarely available at a single institution, while privacy regulations restrict the centralization of patient data.

By Natalia Moreno-Blasco, Anusha Ihalapathirana, Pekka Siirtola, Miguel Fernandez-de-Retana