arXiv Machine Learning

Private and interpretable clinical prediction with quantum-inspired tensor train models

The paper demonstrates that publicly available clinical machine learning models, such as logistic regression (LR), pose significant privacy risks because attackers can recover model parameters and identify training cohorts through various membership inference attacks. The authors show that even small cohorts can be reliably identified and that common practices like cross-validation can worsen the risk. To mitigate this, they propose a quantum-inspired defense that tensorizes discretized models into tensor trains (TTs), which obfuscates parameters, preserves accuracy, and maintains interpretability while providing black‑box protection comparable to Differential Privacy.

arXiv Machine Learning
Oct 23

Automated screening of privacy risks in medical AI

The paper introduces a lightweight screening tool that evaluates individual patient vulnerability to membership inference attacks across thousands of medical AI models. By measuring attack scores for each patient, the authors found that certain records consistently rank high in risk regardless of training settings, and that stronger weight decay can reduce overall exposure but not the identity of the most at‑risk patients. The tool uses four small models to flag high‑risk patients before a production model is trained, aiming to integrate privacy assessment into clinical AI data preparation.

By Konstantinos Vrettos, Eleftherios Tzanis, Haridimos Kondylakis, Evangelia E. Vassalou, Florence X. Doo, Michail E. Klontzas
arXiv AI
Oct 1

Aegis: Generative Gradient Masking for Privacy-Preserving Medical Federated Learning

Aegis is a client‑side defense for medical federated learning that protects against model inversion attacks by adding a masking gradient derived from locally synthesized data. The method exploits the fact that attacks fail when the effective batch size exceeds the model’s leakage capacity, turning this bottleneck into a privacy guarantee. Experiments on MNIST, CIFAR‑10, and MedMNIST datasets show that Aegis neutralizes state‑of‑the‑art attacks while preserving model accuracy and adding only modest overhead.

By Chaoyu Zhang, Shanghao Shi, Heng Jin, Ning Wang, Y. Thomas Hou, Wenjing Lou
arXiv AI
Jul 23

SynPre-FL: Synthetic data-driven pretraining integrated Federated Learning training framework

arXiv:2607. 19524v1 Announce Type: cross Abstract: Federated learning (FL) offers a promising approach to privacy-preserving clinical risk prediction, but its deployment remains limited by restricted data sharing, client heterogeneity, class imbalance, and the lack of realistic tabular electronic health record (EHR) benchmarks.

By Akarsh K Nair, Muhammad Arifur Rahman, Nicholas Shopland, Andy Burton, Jun He, Yuan Shen, David Baldwin, Emma O'Dowd, Amna Burzic, Mufti Mahmud, David J. Brown
Hugging Face Trending Papers
Jun 3

Federated Learning for Multi-Center Sepsis Early Prediction with Privacy-Preserving

Privacy-sensitive and distributed characteristics of multi-center medical data bring severe obstacles to centralized modeling for accurate early prediction of sepsis. Federated learning (FL) has attracted growing attention as a promising framework for collaborative model development, as it allows multiple institutions to jointly train predictive models without directly sharing or centralizing raw data.

arXiv Machine Learning
Oct 8

Efficient Provably Private Classification with a Tabular Foundation Model

Efficient Provably Private Classification with a Tabular Foundation Model introduces PrivTab, a tabular foundation model that embeds differential privacy directly into its architecture. Pretrained on simulated datasets, PrivTab uses in-context learning to convert sensitive rows into compact, provably private summaries, enabling a single forward pass for classification. The model outperforms private linear and neural‑network baselines under moderate-to-strong privacy, shows negligible membership leakage, maintains well‑calibrated predictions, and reduces dataset fitting time by 10,000×.

By Talal Alrawajfeh, Cristiana Diaconu, Ossi R\"ais\"a, Sebastian Rodriguez Beltran, Yuan He, John Bronskill, Richard E. Turner, Antti Honkela
arXiv AI
Jun 18

PSyGenTAB: A Privacy-Preserving Framework for Synthetic Clinical Tabular Data Generation via Constrained Optimization

arXiv:2606. 18518v1 Announce Type: cross Abstract: The development of medical AI is constrained by limited access to high-quality clinical data due to institutional silos and strict privacy regulations such as HIPAA and GDPR.

By Arshia Ilaty, Hossein Shirazi, Manasi Chitale, Kedar Hegde, Dhanalakshmi Ramesh, Rashmi S. Manjunath, Amir Rahmani, Hajar Homayouni
arXiv Machine Learning
Jun 2

Profiling Privacy Preservation Against Gradient Inversion Attacks in Tabular Federated Learning

arXiv:2606. 00986v1 Announce Type: new Abstract: Federated learning (FL) enables multiple data holders to train machine learning models collaboratively without centralizing raw data, making it useful in privacy sensitive domains such as healthcare and institutional data sharing.

By Ivo Osterberg Nilsson, Maximilian Birr Engvall, Viktor Valadi, Teddy Lazebnik