Phorecaster365: A Human-Supervised Reference Architecture for Hybrid Pharmaceutical Sales Forecasting and Planning Decision Support
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arXiv:2607. 18696v1 Announce Type: new Abstract: AI-native biotechnology companies are often designed by copying human biotech org charts into agent roles.
The paper introduces a formal framework and benchmark for time‑series world models (TSWMs) that separates state, actions, and exogenous inputs, and defines a new metric called mechanism consistency to evaluate whether model predictions move in the expected direction when actions change. Experiments on eight public datasets show that using a frozen latent prediction space and gated output fusion improves prediction accuracy, while prediction error and mechanism consistency often diverge, with the best‑performing models sometimes failing to exhibit consistent directional responses. Adding a directional supervision loss significantly boosts mechanism consistency without affecting mean‑absolute error, providing a practical recipe for building more reliable TSWMs.
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