Parameter-Efficient Fine-Tuning of Foundation Models for Liver Tumor Segmentation in CT
Read the original on arXiv Computer Vision →The Flow has not summarised this story yet — read it at arXiv Computer Vision.
The Flow has not summarised this story yet — read it at arXiv Computer Vision.
The paper introduces two lightweight spectral adapters—Directional Spectral Adapter (DiSECT) and Spectral Instance-Guided Adapter (SiGA)—to adapt the Segment Anything Model (SAM) for accurate segmentation of colorectal liver metastases in contrast‑enhanced CT scans. SiGA achieves the highest single‑point Dice score of 0.77 and performs comparably to a 3D nnU‑Net baseline under no‑prompt inference, while DiSECT requires only 0.14 million trainable parameters. The study evaluates the adapters on 446 CT volumes across various prompting regimes, demonstrating that spectral adapters can efficiently adapt SAM with limited trainable parameters while maintaining strong segmentation accuracy.
The study investigates how few expert-annotated cases are needed to fine‑tune MedSAM3 for abdominal organ segmentation using Low‑Rank Adaptation (LoRA). With only 10 annotated CT or MRI cases, the LoRA‑adapted models achieve performance comparable to specialist systems that require orders of magnitude more data, including reliable gallbladder segmentation and near‑state‑of‑the‑art results for liver, kidneys, and spleen. The approach also generalizes to cardiac segmentation on the Whole Heart dataset, and training takes only 3–5 hours per organ on a single GPU, roughly twice as fast as nnU-Net.
RECIST diameter measurements are widely used for tumor response assessment, but they provide only a limited 2D description of lesion extent. We present LETT-NeXt, a lightweight RECIST-guided model that predicts 3D lesion masks from CT volumes and RECIST markers for the CVPR 2026 Foundation Models for Pan-cancer Segmentation in CT Images competition.
Lumen is a pathology vision‑language model that aligns frozen unimodal foundation models (Virchow2 and BioMedBERT) using rank‑4 adapters and projection heads, training only 0.40% of the total parameters on the QUILT‑1M corpus. It achieves the highest mean chance‑corrected balanced accuracy (0.546) across nine zero‑shot patch benchmarks and demonstrates strong performance on lymph‑node metastasis detection, with AUROC scores of 0.964 internally and 0.955 externally. While it ranks third in cross‑modal retrieval, Lumen’s low‑parameter training yields competitive results at both patch and slide levels.
The study explores how adding anatomical priors and active learning can improve the accuracy of deep learning models for segmenting the Clinical Target Volume (CTV) in gastric cancer radiotherapy. Using 100 retrospective CT scans, an nnU‑Net model trained on 10 expert‑contoured cases was enhanced with voxel‑wise anatomical prior maps and iterative active learning over four rounds. The combined approach raised the mean Dice Similarity Coefficient from 0.84 to 0.87, demonstrating that both techniques individually and together improve segmentation performance and generalizability.
arXiv:2604.27697v2 Announce Type: replace-cross Abstract: Peritoneal metastases (PM) are staged using the surgically determined Peritoneal Cancer Index (sPCI), which requires invasive laparoscopic as...