arXiv Computer Vision By Gustav Schmidt, Philipp Berens, Sarah M\"uller

Ordinal Diffusion Models for Color Fundus Images

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The paper introduces an ordinal latent diffusion model for generating color fundus images that incorporates the ordered structure of diabetic retinopathy (DR) severity, using a scalar disease representation instead of categorical conditioning. Evaluations on the EyePACS dataset show improved visual realism, with reduced Fréchet inception distance for most stages and a higher quadratic weighted κ from 0.79 to 0.87. Interpolation experiments demonstrate the model captures a continuous spectrum of disease progression derived from coarse, ordered labels.

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