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Native space based pipelines outperform template space based pipeline in subcortical segmentation

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Accurate segmentation of subcortical regions is critical for neurosurgical planning and functional research. Most automated methods rely on template space coregistration, which may compromise patient-specific accuracy, particularly in small structures.

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arXiv Computer Vision
Sep 25

When Misalignment Becomes Supervision: Structured Label Noise in Supervised Synthetic CT Generation

The paper examines how residual misalignments from registration procedures introduce structured label noise in supervised synthetic CT (sCT) generation. It shows that voxel‑wise metrics are heavily influenced by the consistency between training and evaluation registrations, and that training with anatomically consistent registrations reduces variability and improves robustness. Introducing a perceptual loss based on a pretrained Segment Anything encoder yields sharper, more anatomically coherent sCT and highlights the need for anatomy‑oriented evaluation.

By Valentin Boussot, Cedric Hemon, Caroline Lafond, Jean-Claude Nunes, Jean-Louis Dillenseger
arXiv Computer Vision
Sep 4

Improving Clinical Target Volume Segmentation Accuracy using Anatomical Priors and Active Learning for the AGITG TOPGEAR Clinical Trial

The study explores how adding anatomical priors and active learning can improve the accuracy of deep learning models for segmenting the Clinical Target Volume (CTV) in gastric cancer radiotherapy. Using 100 retrospective CT scans, an nnU‑Net model trained on 10 expert‑contoured cases was enhanced with voxel‑wise anatomical prior maps and iterative active learning over four rounds. The combined approach raised the mean Dice Similarity Coefficient from 0.84 to 0.87, demonstrating that both techniques individually and together improve segmentation performance and generalizability.

By Phillip Chlap, Mark Lee, Trevor Leong, Matthew Field, Jason Dowling, Hang Min, Julie Chu, Jennifer Tan, Phillip K. Tran, Tomas Kron, Annette Haworth, Martin A. Ebert, Shalini K. Vinod, Lois Holloway
arXiv Computer Vision
Sep 2

CMRVision: A Foundation Model for Cardiac MR Image Analysis

CMRVision is a cardiac magnetic resonance (CMR) foundation model trained with DINOv3-style self‑supervised learning on 36 million multi‑center, multi‑sequence CMR images. It outperforms prior natural‑image, medical‑image, supervised, and CMR baselines on multi‑task segmentation (cine, LGE, mapping) and cine view classification, achieving Dice scores of 0.940–0.967 for LV and 0.855–0.905 for myocardium, and a zero‑shot Dice of 0.692 on unseen LGE long‑axis views. The model demonstrates robust cross‑view generalization and highest average accuracy (0.906) for cine view classification.

By Athira J. Jacob, Puneet Sharma, Daniel Rueckert
arXiv Computer Vision
Aug 28

DALE-CT: Depth-Aware 2D Slice Encoders Learn an Anatomical World Model of Chest CT

DALE-CT introduces depth‑aware 2D slice encoders that learn an anatomical world model of chest CT scans without 3D or positional supervision. By sampling self‑supervised views across a physical $z$‑axis slab, the encoder captures how anatomy changes between neighboring slices, enabling it to recover slice ordering and distinguish slices by anatomy alone. The model, trained on a large 287k‑scan corpus, achieves state‑of‑the‑art performance on CT‑RATE and is released with full code and evaluation tools.

By Evan W. Damron, Mahmut S. Gokmen, Mitchell A. Klusty, Caroline N. Leach, Emily B. Collier, V. K. Cody Bumgardner
arXiv Machine Learning
Jun 16

Lesion-DDPM: Lesion-Enhanced 3D Diffusion for MS MRI Synthesis

arXiv:2606. 15457v1 Announce Type: cross Abstract: 3D FLAIR MRI is widely recommended as one of the standard MRI sequences for brain imaging in multiple sclerosis (MS), but publicly available MS datasets remain relatively small and vary across scanners, acquisition protocols, and lesion patterns.

By Weidong Zhang, Yongchan Jung, Shafayat Mowla Anik, Furen Xiao, Vasudevan Janarthanan, Enkhzaya Chuluunbaatar, Byeong Kil Lee, Jeeho Ryoo