Brain4FMs is a unified benchmark for evaluating brain foundation models (BFMs) on both scalp EEG and intracranial EEG (iEEG). It incorporates 17 representative models and 21 public datasets spanning clinical diagnosis, sleep staging, communication, and affective computing, and offers dataset-aware preprocessing, cross‑subject evaluation, and standardized downstream workflows. The benchmark highlights that no single BFM consistently outperforms others across all tasks, modalities, and adaptation protocols, prompting further exploratory analyses of model‑specific spatial, spectral, and discrete representations.
By Fanqi Shen, Enhong Yang, Jiahe Li, Junru Hong, Xiaoran Pan, Zhizhang Yuan, Meng Li, Yang Yang
arXiv:2606. 19888v1 Announce Type: cross Abstract: Modeling long-sequence medical time series data, such as electrocardiograms (ECG), poses significant challenges due to high sampling rates, multichannel signal complexity, inherent noise, and limited labeled data.
By Feng Wu, Harsh Deep, Eric Lehman, Sanyam Kapoor, Guoshuai Zhao, Rahul Krishnan, Gari Clifford, Li-wei H Lehman
arXiv:2506.20354v3 Announce Type: replace-cross
Abstract: Learning from multi-variate time-series with heterogeneous channel configurations remains a fundamental challenge for deep neural networks, p...
By Francesco Carzaniga, Michael Hersche, Abu Sebastian, Kaspar Schindler, Abbas Rahimi
The paper presents a diagnostic framework for Alzheimer’s disease that uses the Large Brain Model (LaBraM), a foundation model pretrained on over 2,500 hours of EEG data, to generate high‑dimensional latent embeddings. These embeddings are fed into a non‑linear Random Forest classifier, achieving an ROC‑AUC of 89.36% ± 3.49%, PR AUC of 81.45% ± 4.43%, and Balanced Accuracy of 82.44% ± 4.34% in a subject‑independent 5‑fold cross‑validation setting, using only 8‑second EEG segments. Post‑hoc occlusion and neurophysiological alignment analyses confirm that the model captures clinically validated biomarkers such as occipital‑frontal Alpha and Theta rhythm degradation and correlates with cognitive performance and clinical severity.
By Maggie Lin, Chung-Lin Hou, Tzyy-Ping Jung
arXiv:2507. 12645v1 Announce Type: cross Abstract: The increasing need for accurate and unified analysis of diverse biological signals, such as ECG and EEG, is paramount for comprehensive patient assessment, especially in synchronous monitoring.
By Mohammed Guhdar, Ramadhan J. Mstafa, Abdulhakeem O. Mohammed
arXiv:2607. 25244v1 Announce Type: new Abstract: Foundation models for 12-lead electrocardiograms (ECGs) transfer well across clinical tasks, but the physiological knowledge encoded in their representations remains opaque.
By Yixuan Duan, Arjun Naik, Sadeer Al-Kindi, Wei Qiu