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arXiv:2511.15188v3 Announce Type: replace Abstract: Accurate brain-age estimation from structural MRI provides a valuable biomarker for studying healthy aging and neurodegenerative disease. We propos...
FiberGeoText (FGT) is a vision‑language model that clusters short‑range superficial white matter streamlines from ultra‑high‑resolution diffusion MRI into population‑level groups. It jointly encodes each streamline’s 3‑D trajectory, cortical anatomical context (via text from multiple parcellation schemes), and shape, using a pretrained large language model to unify heterogeneous anatomical descriptions. Evaluations on 0.76 mm diffusion data show that FGT outperforms state‑of‑the‑art methods in cortical parcel coherence, shape consistency, cluster‑size consistency, and cross‑subject correspondence, and it generalizes well to unseen subjects, recovering 96.7 % of learned clusters.
arXiv:2606. 09893v1 Announce Type: cross Abstract: Diffusion MRI (dMRI) tractography is the only noninvasive approach for mapping white-matter pathways in the living human brain.
The study investigates whether a compact, supervised 3D CNN pretrained for brain‑age prediction can act as a reusable foundation model for various Alzheimer's‑related neuroimaging tasks. By freezing the 7.18 million weights and adding only ~1 % of trainable parameters via Low‑Rank Adaptation, the model achieved high performance across six experiments, including dementia classification, MCI progression prediction, amyloid positivity detection, and volume estimation of hippocampal and white matter hypointensities. The results demonstrate that the pretrained brain‑age model generalizes well to new datasets without retraining, offering a data‑efficient alternative to larger networks.
The paper introduces DB‑SUiT, a surface‑based diffusion bridge that translates cortical MRI to PET images directly on the cortical manifold. It employs a conditional spherical U‑shaped vision Transformer to capture multi‑scale surface features and long‑range dependencies while incorporating demographic and subcortical information. Evaluations on two dementia datasets show that the synthesized PET surfaces outperform MRI and PET volumes in automated classification and achieve high diagnostic accuracy in a blinded reader study.
The paper introduces a two-stage multi‑modal MRI framework that processes different MRI modalities independently before integrating them through late fusion. First, the model estimates a probability distribution over six developmental stages, then it predicts age using probability‑weighted, stage‑specialized experts. Experiments across nine datasets—from fetal to elderly—show the method outperforms existing baselines, reducing mean absolute error by 13% and 78% in in‑domain and out‑of‑domain settings, and multi‑modal integration yields 12‑13% performance gains. Analysis on ADNI clinical groups indicates that the predicted brain age gap could help characterize Alzheimer’s‑related brain aging.