arXiv:2609.14124v1 Announce Type: cross
Abstract: Medical image analysis is often hindered by biased datasets, which can lead to biased models and limited clinical applicability. A promising strategy...
By Yasin Ibrahim, Robin J. Evans, Konstantinos Kamnitsas
arXiv:2609.24879v1 Announce Type: new
Abstract: Counterfactual image generation answers questions about how a subject would have looked under retrospective, hypothetical scenarios. Recent methods hav...
By Xiaodan Xing, Rajat R. Rasal, Julia A. Meister, Sara Ghorayeb, Galvin Khara, Jessica Schrouff
CausalProfiler is a synthetic benchmark generator designed to evaluate causal machine learning (Causal ML) methods more rigorously and transparently. It randomly samples causal models, data, queries, and ground truths based on explicit design choices across observation, intervention, and counterfactual reasoning levels, providing coverage guarantees and transparent assumptions. The authors demonstrate its utility by testing several state‑of‑the‑art methods under diverse conditions, both within and outside the identification regime, highlighting the insights CausalProfiler can reveal.
By Panayiotis Panayiotou, Audrey Poinsot, Alessandro Leite, Nicolas Chesneau, Marc Schoenauer, \"Ozg\"ur \c{S}im\c{s}ek
The paper introduces a formal framework that uses symmetries in data to keep causal mechanisms invariant, providing a simple and general mathematical language for causal reasoning. It outlines how to describe models and queries, and presents strategies for rigorously identifying causal effects from data within this framework. The approach reproduces known results for IID data and extends causal analysis to non‑IID settings, complex queries beyond do‑ or soft‑interventions, and incorporates missing data, transfer, and robustness considerations.
By Martin Rabel, Jakob Runge
The paper evaluates causal representation learning (CRL) methods on a controlled optical experiment where the true causal factors are known. All selected methods fail to reliably recover these factors, even when the data-generating process is simplified to a synthetic version. The study highlights reproducibility issues and the importance of mixing function assumptions, underscoring the gap between theoretical promise and practical performance of CRL techniques.
By Juan L. Gamella, Simon Bing, Jakob Runge
Modern deep learning and AI-assisted code generation are lowering the technical barrier to building mathematical models of biological systems, enabling researchers with domain expertise to create semi-mechanistic, hybrid models that combine prior knowledge with learned structure. However, the predictive success of these grey-box models does not guarantee that the inferred mechanisms truly reflect the underlying biological processes, as the learned components can mask errors in the mechanistic part. To address this ambiguity, the paper proposes using causal inference to identify which causal relationships are discernible from data and knowledge, and ensemble analyses to quantify uncertainty across models that fit the data equally well, thereby clarifying what is supported, what remains uncertain, and which experiments could resolve the remaining questions.
By Marvin van Aalst (Computational Life Science, Faculty of Mathematics and Natural Sciences, RWTH Aachen University, Germany), Ad\`ele H. Ribeiro (Causal and Explainable Artificial Intelligence in Life Sciences, Faculty of Mathematics and Natural Sciences, RWTH Aachen University, Germany, Center for Computational Life Sciences, RWTH Aachen University, Germany), Anna Matuszy\'nska (Computational Life Science, Faculty of Mathematics and Natural Sciences, RWTH Aachen University, Germany, Center for Computational Life Sciences, RWTH Aachen University, Germany)