The paper introduces Term2Note, a method for generating full-length clinical notes under differential privacy constraints. It separates content and form, conditioning note sections on medical terms and applying distinct DP protections to terms and notes, followed by a DP quality maximizer. Experiments show that the synthetic notes closely match real clinical notes in statistical properties, and models trained on them perform comparably to those trained on real data, outperforming existing DP text generation baselines.
By Yuping Wu, Viktor Schlegel, Warren Del-Pinto, Srinivasan Nandakumar, Iqra Zahid, Yidan Sun, Hai Li, Usama Farghaly Omar, Amirah Jasmine, Arun-Kumar Kaliya-Perumal, Chun Shen Tham, Gabriel Connors, Anil A Bharath, Goran Nenadic
arXiv:2608.23248v1 Announce Type: cross
Abstract: Traditional clinical prediction models rely on task-specific pipelines and curated, structured data, which scale poorly and underutilize unstructured...
By Siri Willems, James Butterworth, Lore Goetschalckx, Peter Vrancx, Philippe Modard, Elke Giets, Ludovic Denoyer
arXiv:2310. 16152v5 Announce Type: replace-cross Abstract: Federated learning (FL) has become a key component in various language modeling applications such as machine translation, next-word prediction, and medical record analysis.
By Md Rafi Ur Rashid, Vishnu Asutosh Dasu, Kang Gu, Najrin Sultana, Shagufta Mehnaz
arXiv:2606. 17110v1 Announce Type: cross Abstract: Large Language Models are increasingly trained on proprietary or sensitive data, from private healthcare and financial records to user conversations containing secrets.
By Md Abdullah Al Mamun, Ngoc Phu Doan, Pedram Zaree, Ihsen Alouani, Nael Abu-Ghazaleh
The paper introduces a comprehensive privacy evaluation framework for genomic language models (GLMs) that quantifies memorization risks using perplexity-based detection, canary sequence extraction, and membership inference. By planting canary sequences at different repetition rates in synthetic and real datasets, the authors systematically assess how repetition, model capacity, and training dynamics affect memorization across various GLM architectures. The study demonstrates that GLMs do memorize training data to varying degrees and that no single attack method fully captures this risk, highlighting the necessity of multi-vector privacy auditing for genomic AI systems.
By Alexander Nemecek, Wenbiao Li, Xiaoqian Jiang, Jaideep Vaidya, Erman Ayday
The paper examines how supervised fine-tuning (SFT) of large language models can leak personally identifiable information (PII) when the fine-tuning data contains user-provided sensitive details. It introduces COVA, a coverage-aware decoding algorithm that improves targeted PII reconstruction from SFT models, especially when an adversary has limited contextual knowledge about a target. Experiments on medical and legal Q&A datasets show that even small proprietary SFT datasets can lead to significant privacy leakage via PII reconstruction.
By Sae Furukawa, Alina Oprea
arXiv:2606. 26879v1 Announce Type: new Abstract: Synthetic data is increasingly used to enable the development and evaluation of AI systems in domains where access to real-world data is restricted.
By William Poulett
The paper introduces MIMIC-DOS, a dataset derived from MIMIC-IV that focuses on ICU cases where patient symptoms and medical signs are discordant. It presents CARE, a privacy‑compliant multi‑stage agentic reasoning framework that uses a proprietary LLM to generate structured categories and transitions, while a local LLM performs evidence acquisition and decision‑making. In retrospective evaluations on MIMIC‑DOS, CARE outperforms other LLMs and agentic workflows, demonstrating stronger handling of conflicting clinical evidence while preserving patient privacy.
By Haochen Liu, Weien Li, Rui Song, Zeyu Li, Chun Jason Xue, Xiao-Yang Liu, Sam Nallaperuma-Herzberg, Xue Liu, Ye Yuan
arXiv:2608. 07705v1 Announce Type: new Abstract: Clinical foundation models trained on large-scale patient data are increasingly used for decision support, screening, and public health.
By Sana Tonekaboni, Lena Stempfle, Sasha Ronaghi, Corinna Coupette, I. Glenn Cohen, Emily Alsentzer, Marzyeh Ghassemi
arXiv:2606. 16952v2 Announce Type: replace-cross Abstract: The rapid adoption of generative AI and Large Language Models (LLMs) has spurred interest in synthetic data as a privacy-preserving alternative to sensitive real-world datasets.
By Kareem Amin, Rudrajit Das, Alessandro Epasto, Adel Javanmard, Dennis Kraft, M\'onica Ribero, Sergei Vassilvitskii
Synthetic data is increasingly used to enable the development and evaluation of AI systems in domains where access to real-world data is restricted. In healthcare, clinical documentation presents particular challenges due to its sensitivity.
arXiv:2606. 18782v1 Announce Type: cross Abstract: Large Language Models are increasingly applied to sensitive domains that require redaction of personally identifiable information (PII).
By Sean Brynj\'olfsson, Shashvat Jayakrishnan, Esha Sali, Diptanshu Purwar, Madhav Aggarwal