arXiv AI

Hindsight Bias in Clinical Temporal Reasoning: How Future Data Exposure Affects Large Language Model Judgment

The paper introduces a paired benchmark to detect hindsight bias in clinical language models by comparing model responses to questions posed at a clinically relevant cutoff versus the full timeline. It uses 171 case reports (40 sepsis, 131 GLP‑1/diabetes) with both human‑annotated and LLM‑generated time‑series data, evaluating accuracy, hindsight trap rate, answer instability rate, and hindsight bias rate. Results show that exposing models to the full timeline consistently increases hindsight bias, while truncating the timeline mitigates bias without sacrificing accuracy.

arXiv AI
Jun 9

TRIAGE: Dialectical Reasoning for Explainable Risk Prediction on Irregularly Sampled Medical Time Series with LLMs

arXiv:2606. 09030v1 Announce Type: cross Abstract: Clinical early warning systems built on electronic health records, in which clinical observations are recorded as irregularly sampled medical time series (ISMTS), must deliver both calibrated risk scores for patient triage and interpretable rationales that clinicians can verify.

By Hyeongwon Jang, Gyouk Chu, Changhun Kim, Joonhyung Park, Hangyul Yoon, Eunho Yang
arXiv AI
Aug 25

SDoH-Aware Narrative Anchoring Bias in Medical LLMs for Trustworthy Clinical Decision Support

The paper investigates how medical large language models (LLMs) may exhibit narrative anchoring bias when presented with the same clinical case in different patient voices. Using the NarrativeShield SDoH MedQA dataset, the authors evaluate three Qwen2.5 instruction‑tuned LLMs (1.5B, 3B, 7B) on 300 clinical cases, reporting metrics such as persona‑level accuracy, counterfactual consistency, correct consistency, and narrative sensitivity error. The 7B model achieves the highest accuracy (56.33 %) and correct consistency (40.33 %), yet narrative sensitivity errors remain substantial (31.67 %).

By Ahnaf Atef Choudhury, Ramkrishna Saha
arXiv AI
Jul 16

Ask Before You Diagnose: Safe-Psych, a Sequential Evaluation Benchmark for LLMs in Psychiatry

arXiv:2607. 13036v1 Announce Type: cross Abstract: Large language models (LLMs) are increasingly used for decision support in healthcare, but clinical evidence is often incomplete or evolving.

By Oriana Presacan, Andreea Grama, Larisa Irimin\u{a}, Alireza Nik, Jaya Ojha, Vajira Thambawita, Ciprian I. B\u{a}cil\u{a}, Bogdan Ionescu, Michael A. Riegler
arXiv Computation and Language
Sep 22

LLMs Anchor on Chief Complaint and Fail to Integrate Evidence in Sequential Clinical Triage

The study evaluates large language models (LLMs) on sequential emergency department triage, where acuity labels are predicted from progressively longer nurse‑patient conversations. Six LLMs were tested at five checkpoints on simulated and physician‑authored dialogues, showing a decline from moderate‑to‑substantial agreement on full records to only fair‑to‑moderate agreement at each checkpoint. The models consistently anchor on chief complaint exchanges and fail to integrate later evidence, yielding low agreement with clinicians (QWK 0.295 vs. 0.887‑0.929) and concentrating predictions on ESI‑2 and ESI‑3. whyItMatters":"The findings reveal that LLMs, despite strong offline performance, cannot reliably handle the sequential nature of real‑time triage, highlighting a critical gap for safe deployment in emergency settings."

By Dipankar Srirag, Haokai Zhao, Ashutosh Kumar, Eleanor Hopper, Michael Dalton, Quoc Dung Nguyen, Aditya Joshi, Salil S. Kanhere, Padmanesan Narasimhan
arXiv AI
Sep 7

MMTClinic: Multimodal, Multilingual Time Series Question Answering and Reasoning Benchmark for Clinical Domain

MMTClinic is a new benchmark that tests large language models on complex reasoning and question‑answering tasks involving clinical time‑series data. It combines text, medical images, and multivariate physiological signals to create 30,000 QA pairs—including 15,000 multiple‑choice and 15,000 open‑ended questions—in five languages (English, Hindi, Bengali, Marathi, and Tamil). The benchmark covers mortality prediction, heart‑rate forecasting, and SOFA score estimation, and evaluates 13 state‑of‑the‑art LLMs across zero‑shot, few‑shot, and chain‑of‑thought settings, revealing significant performance gaps across tasks, languages, and modalities.

By Sourav Malakar, Harshit Nigam, Akash Ghosh, Sriparna Saha, Amlan Chakrabarti, Saptarsi Goswami, Priti Singh
arXiv AI
Sep 18

CliniCIRCA: A Modular LLM Framework for Constructing Longitudinal Mental Health Patient Journeys from Raw EHR Narratives

CliniCIRCA is a modular large‑language‑model framework that reconstructs longitudinal mental‑health patient journeys from raw electronic health record narratives. It temporally classifies clinical events in unstructured discharge summaries without explicit timestamps, producing 15,891 tagged events from 52 summaries and correcting 629 errors to create verified gold‑standard timelines. The framework then generates temporally grounded summaries, compressing each source by 1.52×, and scales to produce 1,000 silver‑standard timelines for training, showing that instruction tuning improves event extraction, temporal tagging, and summarization across models.

By Aiwei Ivy Zhang, Nimra Ishfaq, Mohit Chandra, Santiago Alvarez Lesmes, Adam Coscia, Khatiya Chelidze Moon, Xiaohan Ding, Munmun De Choudhury