arXiv:2604. 04958v3 Announce Type: replace-cross Abstract: Recent work suggests that large-scale, multi-animal modeling can significantly improve neural recording analysis.
By Xinhong Xu, Yimeng Zhang, Qichen Qian, Yuanlong Zhang
arXiv:2607. 09754v1 Announce Type: cross Abstract: Large-scale, multi-subject widefield calcium imaging provides unprecedented access to brain-wide cortical dynamics.
By Mohammad Hosseini, Eray Erturk, Saba Hashemi, Maryam M. Shanechi
BrainWideBench is a benchmark that evaluates across‑animal transfer on multi‑region neural recordings from 139 mice, covering 276 brain regions. It comprises three task suites—behavior decoding, neural activity prediction, and anatomical organization recovery—to test whether learned representations support diverse downstream objectives. The benchmark shows that while pretraining improves performance over single‑session baselines, current methods vary in transfer ability and none perform uniformly well across all suites, highlighting the challenge of developing general‑purpose neural representations.
By Alexandre Andre, Shivashriganesh P. Mahato, Vinam Arora, Keshav Balaji, Divyansha Lachi, Nanda H. Krishna, Jingyun Xiao, Yizi Zhang, Ximeng Mao, Wenrui Ma, Han Yu, International Brain Laboratory, Daniel Birman, Niccol\`o Bonacchi, Gaelle A. Chapuis, Joana A. Catarino, Felicia Davatolhagh, Mayo Faulkner, Laura Freitas-Silva, Fei Hu, Julia M. Huntenburg, Anup Khanal, In\^es Laranjeira, Petrina Lau, Guido T. Meijer, Nathaniel J. Miska, Jean-Paul Noel, Alejandro Pan-Vazquez, Georg Raiser, Cyrille Rossant, Karolina Z. Socha, Anne E. Urai, Miles J. Wells, Steven J. West, Olivier Winter, Blake Richards, Guillaume Lajoie, Cole Hurwitz, Mehdi Azabou, Matthew R. Whiteway, Liam Paninski, Eva L. Dyer
arXiv:2412.07264v2 Announce Type: replace-cross
Abstract: Understanding complex animal behaviors hinges on deciphering the neural activity patterns within brain circuits, making the ability to foreca...
By Salvatore Calcagno, Isaak Kavasidis, Simone Palazzo, Marco Brondi, Luca Sit\`a, Giacomo Turri, Daniela Giordano, Vladimir R. Kostic, Tommaso Fellin, Massimiliano Pontil, Concetto Spampinato
arXiv:2607. 14086v1 Announce Type: new Abstract: Robust and accurate neural decoders are integral to neurotechnologies such as brain-computer interfaces and closed-loop experiments.
By Ximeng Mao, Nanda H. Krishna, Avery Hee-Woon Ryoo, Matthew G. Perich, Guillaume Lajoie
The paper introduces Latent Drift, a generative forecasting framework that predicts slow-evolving neurodegenerative disease progression by learning changes in a compressed semantic representation rather than full-resolution anatomy. It addresses two failure modes—identity collapse and continuous interpolation trap—by removing pixel-level identity from the prediction target and applying Finite Scalar Quantization to suppress high-frequency nuisance fluctuations. Experiments on longitudinal 3D brain MRI demonstrate that Latent Drift outperforms diffusion and autoregressive transformer baselines in both generative fidelity and clinically relevant metrics.
By Yuxiang Feng, Juncheng Wang, Chao Xu, Wenlong Hou, Huihan Wang, Yijie Qian, Yang Liu, Baigui Sun, Yong Liu, Shujun Wang