arXiv AI

CalM: A Self-Supervised Foundation Model for Population Dynamics in Calcium Imaging Data

arXiv:2604. 04958v3 Announce Type: replace-cross Abstract: Recent work suggests that large-scale, multi-animal modeling can significantly improve neural recording analysis.

arXiv AI
Jul 28

CAPT: A Multi-task Continuous Autoregressive Transformer enabling Cross-dataset and Cross-species Transfer for Calcium Population Dynamics

arXiv:2607. 23258v1 Announce Type: new Abstract: Large-scale calcium imaging has created an opportunity to build foundation-style models for neural population dynamics, but a central question remains unresolved: \textbf{whether a model pretrained on one collection of recordings can generalize to new datasets, experimental paradigms, and even species.

By Xinhong Xu, Yimeng Zhang, Yuanlong Zhang
arXiv Computer Vision
Aug 25

QuantFormer: Learning to Quantize for Neural Activity Forecasting in Mouse Visual Cortex

arXiv:2412.07264v2 Announce Type: replace-cross Abstract: Understanding complex animal behaviors hinges on deciphering the neural activity patterns within brain circuits, making the ability to foreca...

By Salvatore Calcagno, Isaak Kavasidis, Simone Palazzo, Marco Brondi, Luca Sit\`a, Giacomo Turri, Daniela Giordano, Vladimir R. Kostic, Tommaso Fellin, Massimiliano Pontil, Concetto Spampinato
arXiv Machine Learning
Sep 21

BrainWideBench: Benchmarking large-scale pretraining and across-animal transfer in multi-region neural recordings

BrainWideBench is a benchmark that evaluates across‑animal transfer on multi‑region neural recordings from 139 mice, covering 276 brain regions. It comprises three task suites—behavior decoding, neural activity prediction, and anatomical organization recovery—to test whether learned representations support diverse downstream objectives. The benchmark shows that while pretraining improves performance over single‑session baselines, current methods vary in transfer ability and none perform uniformly well across all suites, highlighting the challenge of developing general‑purpose neural representations.

By Alexandre Andre, Shivashriganesh P. Mahato, Vinam Arora, Keshav Balaji, Divyansha Lachi, Nanda H. Krishna, Jingyun Xiao, Yizi Zhang, Ximeng Mao, Wenrui Ma, Han Yu, International Brain Laboratory, Daniel Birman, Niccol\`o Bonacchi, Gaelle A. Chapuis, Joana A. Catarino, Felicia Davatolhagh, Mayo Faulkner, Laura Freitas-Silva, Fei Hu, Julia M. Huntenburg, Anup Khanal, In\^es Laranjeira, Petrina Lau, Guido T. Meijer, Nathaniel J. Miska, Jean-Paul Noel, Alejandro Pan-Vazquez, Georg Raiser, Cyrille Rossant, Karolina Z. Socha, Anne E. Urai, Miles J. Wells, Steven J. West, Olivier Winter, Blake Richards, Guillaume Lajoie, Cole Hurwitz, Mehdi Azabou, Matthew R. Whiteway, Liam Paninski, Eva L. Dyer
arXiv Machine Learning
Jun 30

BrainJanus: A Unified Model for Understanding and Generation across Brain, Vision, and Language

arXiv:2606. 30319v1 Announce Type: cross Abstract: Modeling the bidirectional correspondence between external sensory stimuli and internal neural activity has emerged as a critical frontier in neuroscience.

By Haitao Wu, Qirui Zhang, Zhouheng Yao, Shangquan Sun, Qihao Zheng, Mianxin Liu, Chi Zhang, Wanli Ouyang, Chunfeng Song, Changqing Zhang, Jiamin Wu