arXiv AI By Rongbin Li, Wenbo Chen, Zhao Li, Rodrigo Munoz-Castaneda, Jinbo Li, Neha S. Maurya, Arnav Solanki, Huan He, Hanwen Xing, Meaghan Ramlakhan, Zachary Wise, Nelson Johansen, Zhuhao Wu, Hua Xu, Michael Hawrylycz, W. Jim Zheng

BRAINCELL-AID: An Agentic AI Created Brain Cell Type Resource for Community Annotation

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arXiv:2510. 17064v4 Announce Type: replace Abstract: Single-cell RNA sequencing has transformed our ability to identify diverse cell types and their transcriptomic signatures.

Machine-generated by The Flow from the publisher's headline and feed description — not written or checked by a human. The full article lives at arXiv AI.

arXiv AI
Aug 3

ELISA: An Interpretable Hybrid Generative AI Agent for Expression-Grounded Discovery in Single-Cell Genomics

arXiv:2603. 11872v3 Announce Type: replace-cross Abstract: Translating single-cell RNA sequencing (scRNA-seq) data into mechanistic biological hypotheses remains a critical bottleneck, as agentic AI systems lack direct access to transcriptomic representations while expression foundation models remain opaque to natural language.

By Omar Coser
arXiv Computation and Language
Sep 3

NS-Copilot: An LLM-Driven Agent System for Autonomous Neuroscience Analysis

NS-Copilot is a large‑language‑model driven multi‑agent system designed to automate neuroscience data analysis. It integrates domain‑specific pre‑trained models for modalities such as EEG and extracellular spike data, and uses a natural‑language interface to orchestrate agents that plan, generate code, and synthesize results. In benchmarks on Alzheimer’s, Parkinson’s, and working‑memory spike decoding, the system consistently outperformed strong baselines across multiple trials.

By Wuche Liu, Yiran Qiao, Linlin Hou, Rui Yang, Shusen Pu, Song Wang, Jing Ma
arXiv AI
6d ago

FlyAOC: Evaluating Agentic Ontology Curation of Drosophila Scientific Knowledge Bases

FlyAOC is a benchmark that tests AI agents on end‑to‑end ontology curation of Drosophila scientific literature. Given a gene symbol, a brief description, a large paper corpus, and ontology resources, agents must search for evidence and produce structured annotations such as function terms, expression patterns, and historical synonyms. The benchmark contains 7,397 expert‑curated annotations across 100 genes and evaluates different agent harnesses, revealing system‑level failure modes that single‑task evaluations miss.

By Xingjian Zhang, Sophia Moylan, Ziyang Xiong, Qiaozhu Mei, Yichen Luo, Jiaqi W. Ma
arXiv Machine Learning
Jun 18

Self-Driving Datasets: From 20 Million Papers to Nuanced Biomedical Knowledge at Scale

arXiv:2605. 07022v3 Announce Type: replace Abstract: Manually curated biomedical repositories -- spanning bioactivity, genomics, and chemistry -- are expensive to maintain, lag behind primary literature, and discard experimental context, obscuring nuances needed to assess data correctness and coverage.

By Haydn Jones, Yimeng Zeng, Alden Rose, Li S. Yifei, Yining Huang, Kaiwen Wu, Jiaming Liang, Maggie Ziyu Huan, Yoseph Barash, Cesar de la Fuente-Nunez, Osbert Bastani, Zachary Ives, Mark Yatskar, Jacob R. Gardner
arXiv AI
Jul 13

TheBioCollection: Unified Pre-Training Scale LLM Corpus for Biology

arXiv:2607. 08803v1 Announce Type: cross Abstract: The push toward large language models for biology (BioLM) has created a need for training corpora that can endow models with a genuine understanding of biology.

By Hyunjin Seo, Hyeon Hwang, Gyubok Lee, Jay Shin, Jimin Park, Taesoo Kim, Sanghoon Lee, Hongjoon Ahn, Sungjun Han, Sangwon Jung