arXiv Computer Vision
Aug 28

Automated 2D and 3D Segmentation of AMD and DME Lesions in OCT

This study presents four deep‑learning pipelines—two‑dimensional and three‑dimensional—for segmenting age‑related macular degeneration (AMD) and diabetic macular edema (DME) lesions in optical coherence tomography (OCT) images. The models achieve Dice scores between 0.76 and 0.82 and demonstrate strong volumetric and surface calibration (r_vol, r_surf ≥ 0.97) on an in‑domain validation set. Generalization was assessed on the OLIVES clinical cohort using proxy metrics such as biomarker AUROC, central subfield thickness correlation, and longitudinal concordance, showing that the predictions still track clinical biomarkers outside the training distribution, albeit with reduced strength.

By Lucia Sundberg, Zhihao Zhao, M. Ali Nasseri
arXiv Computer Vision
6d ago

retinalysis-vascx: An explainable software toolbox for the extraction of retinal vascular biomarkers

arXiv:2602.08580v4 Announce Type: replace-cross Abstract: Automatic extraction of retinal vascular biomarkers from color fundus images (CFI) is crucial for large-scale studies of the retinal vasculat...

By Jose D. Vargas Quiros, Michael J. Beyeler, Sofia Ortin Vela, EyeNED Reading Center, Sven Bergmann, Caroline C. W. Klaver, Bart Liefers, VascX Research Consortium
arXiv AI
Aug 20

OptiModNet: A UNet-Transformer Hybrid with Grouped-Query and Channel Attention for Optic Disc and Cup Segmentation

OptiModNet is a lightweight UNet‑Transformer hybrid designed for optic disc and cup segmentation. It incorporates grouped‑query and channel attention across multiple stages, along with an Aggregated Pyramid Loss to improve gradient flow and structural consistency. Evaluated on the REFUGE2 dataset, it surpasses existing methods by over 2.5 % while using only 3.73 GFLOPs and 1.93 M parameters.

By Soumili Ghosh, Debapriya Roy, Aryan Das, Bikash Santra
arXiv Computer Vision
3d ago

Explainable Convolutional Neural Networks for Retinal Fundus Classification and Cutting-Edge Segmentation Models for Retinal Blood Vessels from Fundus Images

The paper presents a two‑pipeline framework for retinal fundus analysis that combines four‑class disease classification with vessel segmentation. It fine‑tunes eight ImageNet‑pretrained CNNs on the FIVES dataset, applies five gradient‑based explanation methods to assess model interpretability, and benchmarks ten U‑Net variants—including transformer‑based and attention‑enhanced architectures—on the FIVES and DRIVE datasets. The best classification results come from ResNet101 (94.17% accuracy), while the strongest segmentation performance is achieved by Attention U‑Net with a ResNet101V2 backbone, improving DRIVE IoU from 60.80% to 64.83%.

By Fatema Tuj Johora Faria, Mukaffi Bin Moin, Pronay Debnath, Asif Iftekher Fahim, Faisal Muhammad Shah