arXiv Computer Vision
Aug 28

Automated 2D and 3D Segmentation of AMD and DME Lesions in OCT

This study presents four deep‑learning pipelines—two‑dimensional and three‑dimensional—for segmenting age‑related macular degeneration (AMD) and diabetic macular edema (DME) lesions in optical coherence tomography (OCT) images. The models achieve Dice scores between 0.76 and 0.82 and demonstrate strong volumetric and surface calibration (r_vol, r_surf ≥ 0.97) on an in‑domain validation set. Generalization was assessed on the OLIVES clinical cohort using proxy metrics such as biomarker AUROC, central subfield thickness correlation, and longitudinal concordance, showing that the predictions still track clinical biomarkers outside the training distribution, albeit with reduced strength.

By Lucia Sundberg, Zhihao Zhao, M. Ali Nasseri
arXiv Computer Vision
Oct 16

FPG-Seg: Annotation-free Retinal Vessel Topology Segmentation

FPG-Seg is an annotation‑free pipeline for retinal vessel segmentation that combines classical vesselness filtering, Bayesian deep learning, and topology‑aware graph reconstruction. It achieves a clDice score of 0.74–0.78, which is 86–98% of the performance of a fully‑supervised baseline, across four benchmark datasets. The work also presents the first performance benchmark of an annotation‑free vessel segmentation method on the FIVES dataset.

By James Willoughby, Irina Voiculescu
arXiv Computer Vision
Sep 1

retinalysis-vascx: An explainable software toolbox for the extraction of retinal vascular biomarkers

arXiv:2602.08580v4 Announce Type: replace-cross Abstract: Automatic extraction of retinal vascular biomarkers from color fundus images (CFI) is crucial for large-scale studies of the retinal vasculat...

By Jose D. Vargas Quiros, Michael J. Beyeler, Sofia Ortin Vela, EyeNED Reading Center, Sven Bergmann, Caroline C. W. Klaver, Bart Liefers, VascX Research Consortium
arXiv AI
Aug 20

OptiModNet: A UNet-Transformer Hybrid with Grouped-Query and Channel Attention for Optic Disc and Cup Segmentation

OptiModNet is a lightweight UNet‑Transformer hybrid designed for optic disc and cup segmentation. It incorporates grouped‑query and channel attention across multiple stages, along with an Aggregated Pyramid Loss to improve gradient flow and structural consistency. Evaluated on the REFUGE2 dataset, it surpasses existing methods by over 2.5 % while using only 3.73 GFLOPs and 1.93 M parameters.

By Soumili Ghosh, Debapriya Roy, Aryan Das, Bikash Santra