AutoMIL is an open‑source framework that automates key steps of multiple instance learning pipelines for whole‑slide image classification, including preprocessing, training, and evaluation. In benchmark tests, it achieved ROC‑AUC scores of 0.94 on UBC‑OCEAN, 0.99 on PCam, and 0.93‑0.96 on a TCGA‑NSCLC subset, matching the performance of specialized pipelines. The framework’s ensembling approach particularly improved results on imbalanced datasets, demonstrating the need for automated pipelines to adapt to dataset characteristics.
arXiv:2502.02707v5 Announce Type: replace Abstract: Multiple Instance Learning (MIL) for whole slide image (WSI) analysis in computational pathology often neglects instance-level learning as supervis...
arXiv:2609.00396v1 Announce Type: new Abstract: Histopathological whole slide images (WSIs) are central to cancer diagnosis, but their gigapixel scale, tissue heterogeneity, weak slide-level supervis...
The paper introduces a denoising mutual knowledge distillation framework for bi-directional multiple instance learning (MIL) applied to whole slide image classification in digital pathology. By integrating instance-level classifiers and masks, the method grounds predictions on supporting patches while mitigating noisy labels. The proposed algorithm enhances both bag- and instance-level performance, as demonstrated on public pathology datasets.
arXiv:2610.28007v1 Announce Type: new Abstract: Pathology foundation models (PFMs) support a wide range of histopathology tasks on whole-slide images through multiple instance learning (MIL). Despite...
arXiv:2607. 14703v1 Announce Type: cross Abstract: Multiple instance learning (MIL) has become the main paradigm for whole-slide image (WSI) analysis in computational pathology.
arXiv:2407.03463v2 Announce Type: replace-cross Abstract: In the realm of self-supervised learning (SSL), conventional wisdom has gravitated towards the utility of massive, general domain datasets fo...
The study investigates whether pathology foundation models (PFMs) carry center-related biases into whole-slide image (WSI) classification. By training models with increasing class-center correlations and evaluating six PFMs across four datasets and two MIL aggregators, the authors introduce the Area Under the Cramér's V Curve (AUCC) to measure both accuracy and degradation due to spurious correlations. Results reveal that center information propagates to WSI predictions, with robustness varying by PFM and MIL strategy, and that ComBat harmonization does not consistently improve robustness.
arXiv:2610.15669v2 Announce Type: replace-cross Abstract: Weak bag-level labels are widely available in computational pathology, whereas reliable instance-level annotations for whole-slide images rem...
arXiv:2606. 27579v1 Announce Type: cross Abstract: Accurate assessment of tumor proportion score (TPS) in non-small cell lung cancer (NSCLC) is critical for treatment planning and prognosis.
The paper introduces a pipeline that uses publicly available whole slide image foundation models (FMs) to automatically triage slides by ranking them based on zero‑shot classification predictions. This approach accurately identifies slides containing the most tumor, achieving top‑2 ranking for patients with up to 43 slides across multiple datasets. The study also proposes a ranked evaluation framework to benchmark FM performance in slide triage.
arXiv:2604. 17376v2 Announce Type: replace-cross Abstract: In today's day and age, we face a challenge in detecting deepfake images because of the fast evolution of modern generative models and the poor generalization capability of existing methods.
arXiv:2609.25500v1 Announce Type: new Abstract: Training data quantity and quality greatly affect object detection model performance, regardless of model architecture. When using object detection mod...