arXiv AI

A Benchmark for Early-stage Parkinson's Disease Detection from Speech

arXiv:2605. 14066v2 Announce Type: replace-cross Abstract: Early-stage Parkinson's disease (EarlyPD) detection from speech is clinically meaningful yet underexplored, and published results are hard to compare because studies differ in datasets, languages, tasks, evaluation protocols, and EarlyPD definitions.

arXiv Computation and Language
Sep 21

Cross-Lingual Parkinson's Disease Severity Assessment Using Pre-trained Speech Embeddings: A Multi-Class Evaluation

The paper evaluates pre‑trained speech embeddings from four state‑of‑the‑art speech foundation models for cross‑lingual Parkinson's disease severity assessment. Experiments span three datasets in zero‑shot and k‑shot settings, showing that these embeddings can transfer meaningfully across languages, though performance varies with dataset characteristics, preprocessing, and adaptation strategy. Misclassifications linked to inter‑speaker variability and atypical speech patterns underscore the need for more robust feature extraction, modeling, and explainability to support reliable clinical insights.

By Simon Pals, Cristian Tejedor-Garcia
arXiv Machine Learning
Sep 16

BenSParX: A Robust Explainable Machine Learning Framework for Parkinson's Disease Detection from Bengali Conversational Speech

BenSparX introduces the first Bengali conversational speech dataset for Parkinson’s disease detection and pairs it with a robust, explainable machine learning framework. The framework uses diverse acoustic features, systematic feature selection, and advanced classifiers, achieving 95.67% accuracy, 95.62% F1, and 0.990 AUC. SHAP analysis is employed to explain feature contributions, and the model outperforms state‑of‑the‑art methods on other language datasets.

By Riad Hossain, Muhammad Ashad Kabir, Arat Ibne Golam Mowla, Animesh Chandra Roy, Ranjit Kumar Ghosh
arXiv Computation and Language
6d ago

Why Alzheimer's Speech Screening Fails to Generalize: Bridging the Deployment Gap via Cross-Corpus Evidence Anchoring

The paper examines why speech‑based screening for Alzheimer’s disease fails to generalize across different languages, tasks, and recording protocols. Using a leave‑one‑corpus‑out evaluation on four datasets, it finds that 59 of 70 interpretable speech features show conflicting patterns between healthy controls and cognitive risk groups, with pause, silence, and speech rate being highly protocol‑sensitive. The authors propose a fusion method that combines XLM‑R text baseline scores with evidence anchors, improving mean speaker AUC to 0.785 and worst‑case AUC to 0.615, and emphasize the importance of auditing feature transferability and reporting worst‑case domain robustness.

By Zijian Lu, Sizhe Liu, Yin Zhang, Jixuan Deng, Xinrong Lin, Xinchen Yuan, Chicheng Jin, Yiping Zuo, Yuanchao Li
arXiv AI
Sep 2

Cleaner Speech, Weaker Generalization: Revisiting Pitt-Derived Benchmarks for Alzheimer's Disease Detection

The study examines how speech preprocessing—such as enhancement, sample selection, and demographic balancing—affects Alzheimer’s disease detection models that use the Pitt Corpus. Experiments reveal that while speech‑enhanced datasets boost in‑domain accuracy, they diminish cross‑dataset robustness and introduce class imbalance and prediction shifts, even when training and testing enhancements are matched. Large audio‑language models show similar sensitivity, indicating that cleaner speech does not guarantee better real‑world performance.

By Luqi Sun, Shreeram Suresh Chandra, Lin Zhang, You-Jin Li, Brian MacWhinney, Yu Tsao, Emily Mower Provost, Berrak Sisman