arXiv AI

Clinical Knowledge Graphs for Chest X-Ray Device Reasoning

The paper introduces an uncertainty‑aware clinical knowledge graph for chest X‑ray device reasoning, capturing device instances, tip estimates, placement assessments, provenance, report events, and temporal links as interconnected evidence. The graph builder processes 30,083 studies from 3,255 patients, producing 914,632 evidence nodes and 884,549 typed relationships, while preserving detailed uncertainty and provenance information for each predicted device. The authors also outline typed data contracts, uncertainty representations, abstention rules, report‑image grounding, and longitudinal query mechanisms, though the current analysis is post‑hoc descriptive and does not yet demonstrate clinical utility.

arXiv AI
Aug 21

MKG-CARE: Case-Aware Reasoning with Multimodal Knowledge Graphs for Explainable Medical Image Diagnosis

arXiv:2605. 22547v3 Announce Type: replace-cross Abstract: Medical image diagnosis has achieved significant progress with deep learning, yet existing methods often rely on isolated visual evidence and lack the ability to effectively leverage similar cases and external knowledge.

By Yiming Xu, Yixuan Liu, Yuhang Zhang, Ling Zheng, Yihan Wang, Qi Song
arXiv Computer Vision
Sep 21

Graph-Augmented Topological Internalization with Dual-Stream Classifiers for Medical Report Generation

The paper introduces GDMRG, a Graph-Augmented Dual-Stream Medical Report Generation framework that incorporates a Topological Knowledge Internalization module using a Graph Convolutional Network to encode disease co-occurrence priors. It employs a dual-stream classifier—one branch generating diagnostic prompts under topological constraints and an auxiliary branch dynamically calibrating decision boundaries for imbalanced samples—alongside a Diagnosis-Guided Spatial Attention mechanism to align visual features with clinical semantics. Experiments on MIMIC-CXR show competitive clinical efficacy and natural language fluency, with strong zero-shot performance on IU X-Ray.

By Moyu Tang, Shangkun Sima, Chupei Tang, Junxiao Kong, Di Wang, Tianchi Lu
arXiv AI
Jun 16

XMedFusion: A Knowledge-Guided Multimodal Perception and Reasoning Framework for Autonomous Medical Systems

arXiv:2606. 14766v1 Announce Type: cross Abstract: Autonomous medical and robotic systems increasingly rely on intelligent perception and reasoning capabilities to interpret visual data and support clinical decision making.

By Hamza Riaz, Arham Haroon, Maha Baig, Muhammad Dawood Rizwan, Muhammad Naseer Bajwa, Muhammad Moazam Fraz
arXiv Machine Learning
Jul 30

Rethinking Clinical Relevance in Chest X-ray Machine Learning: How Evaluation References Define Performance

arXiv:2607. 26333v1 Announce Type: cross Abstract: Chest X-ray (CXR) machine learning relies heavily on automated evaluation using reference standards that aim to approximate clinical judgment.

By Panagiotis Fytas, Ian Selby, Clemens Karner, Judith Babar, Simon Baker, Jake Beckford, Timothy J. Sadler, Shahab Shahipasand, Arthikkaa Thavakumar, John Li Chen, Alex Sawer, Michael Roberts, Jonathan Weir-McCall, J. H. F. Rudd, Carola-Bibiane Sch\"onlieb, Anna Korhonen, Anna Breger
arXiv AI
Sep 10

A radiographic world model for clinical reasoning and evidence generation

The paper introduces MedDream, a radiographic world model that learns a shared continuous latent state from paired chest radiograph-text observations. MedDream outperforms existing diagnostic and generative AI models across eight clinical datasets, improving diagnostic reasoning, resident concordance, and evidence generation. Targeted synthetic augmentation guided by subgroup performance gaps further enhances model performance, particularly for Asian patients.

By Suyang Xi, Songtao Hu, Shansong Wang, Mojtaba Safari, Luke del Balzo, Ehsan Ul Karim, Mingzhe Hu, Kuo Zhang, Tonghe Wang, Ralph R. Weichselbaum, Xiaofeng Yang
arXiv AI
Sep 17

Reporting Practice Matters: The Impact of Reference Choice on Chest X-ray Report Evaluation

The study examines how differences in radiologists’ reporting styles—such as terminology, shorthand, formatting, and detail—affect the evaluation of AI-generated chest X‑ray reports. By quantifying the sensitivity of common metrics to these variations, the authors show that changes in reference reports can shift model rankings. They introduce a taxonomy of reporting variations and a rewriting method, ReRef, that preserves clinical meaning while altering style, and release a validated dataset of paired reference reports to aid future research.

By Daniel P. Jeong, Charles Q. Li, Hossein Hosseiny, Nitya M. Bhalla, Fatma Uyar Morency, Pradeep Ravikumar, Zachary C. Lipton, Michael Oberst
arXiv Machine Learning
Jun 5

A Vision-language Framework for Comparative Reasoning in Radiology

arXiv:2606. 06407v1 Announce Type: cross Abstract: Medical imaging artificial intelligence has achieved strong performance in isolated image interpretation, but remains poorly aligned with radiological practice, where diagnosis and follow-up rely on comparison across prior studies and analogous reference cases.

By Tengfei Zhang, Ziheng Zhao, Lisong Dai, Xiaoman Zhang, Pengcheng Qiu, Ya Zhang, Yanfeng Wang, Weidi Xie
arXiv AI
Jun 19

Scaling Generative Foundation Models for Chest Radiography with Rectified Flow Transformers

arXiv:2606. 19460v1 Announce Type: cross Abstract: We introduce the first generative foundation model for chest radiograph synthesis trained from scratch at the billion-parameter scale.

By Fabio De Sousa Ribeiro, Emma A. M. Stanley, Charles Jones, Tian Xia, Dominic C. Marshall, Laurent Renard Trich\'e, Christopher V. Cosgriff, Panagiotis Dimitrakopoulos, Sotirios A. Tsaftaris, Ben Glocker