arXiv:2412.15957v2 Announce Type: replace-cross
Abstract: The rapid development of large language models (LLMs) has transformed many industries, including healthcare. In practice, hospitals and patie...
By Ruize Shi, Hong Huang, Wei Zhou, Kehan Yin, Kai Zhao, Yun Zhao
arXiv:2607. 12687v1 Announce Type: cross Abstract: LLMs can perform language-based quantitative prediction from unstructured inputs, but remain susceptible to hallucinations and overconfident errors, making it critical to know not only what a model predicts, but when its predictions can be trusted.
By Mehak Dhaliwal, Rasta Tadayon, Andong Hua, Haewon Jeong, Yao Qin
ConsultMind is an uncertainty‑aware framework that automates diagnostic consultation by updating disorder posteriors after each patient response and using posterior uncertainty to guide inquiry and diagnosis. It builds on AutoDisym, a pipeline that constructs a Disorder–Symptom Bayesian Network (DSBN) from diagnostic knowledge and clinical narratives. Across psychiatry, respiratory medicine, fever clinics, and public datasets, AutoDisym produces high‑quality DSBNs and ConsultMind improves diagnostic accuracy and explanation quality, achieving up to 22.15‑point gains in Top‑1 accuracy and 37.89‑point gains in Top‑3 accuracy.
By Xiao Sun, Yuming Yang, Yun Chen, Jiang Zhong, Junnan Zhu, Xinyi Jiang, Haoyang Zeng, Ruirui Chen, Yining Wang, Xinyu Zhou, Rong Tang, Kaiwen Wei
arXiv:2603. 14158v2 Announce Type: replace-cross Abstract: Large language models (LLMs) are entering clinical workflows, yet evaluations rarely assess how clinician reasoning shapes model behavior during clinical interactions.
By Ivan Lopez, Selin S. Everett, Bryan J. Bunning, April S. Liang, Dong Han Yao, Shivam C. Vedak, Kameron C. Black, Sophie Ostmeier, Stephen P. Ma, Emily Alsentzer, Jonathan H. Chen, Akshay S. Chaudhari, Eric Horvitz
arXiv:2607. 13036v1 Announce Type: cross Abstract: Large language models (LLMs) are increasingly used for decision support in healthcare, but clinical evidence is often incomplete or evolving.
By Oriana Presacan, Andreea Grama, Larisa Irimin\u{a}, Alireza Nik, Jaya Ojha, Vajira Thambawita, Ciprian I. B\u{a}cil\u{a}, Bogdan Ionescu, Michael A. Riegler
arXiv:2608. 16831v1 Announce Type: new Abstract: Generative pretraining established reusable task representations; later work on language-based task conditioning and in-context learning showed that a fixed model could adapt its behavior from instructions and demonstrations.
By Minh-Ha Nguyen, Cathy Shyr
arXiv:2509.19375v2 Announce Type: replace-cross
Abstract: Large language models are increasingly used for clinical text classification, where overconfident misclassifications can directly affect pati...
By Mridul Sharma, Adeetya Patel, Zaneta D' Souza, Samira Abbasgholizadeh Rahimi, Siva Reddy, Sreenath Madathil
The paper discusses how autonomous AI systems are moving from advisory to agentic roles in medication prescribing, citing recent U.S. legislation and a Utah pilot program. It argues that three architectural features—calibrated per‑prediction confidence, clear differentiation between epistemic and aleatoric uncertainty, and inferential transparency—are essential for safe autonomous prescribing. A survey of 136 U.S. clinicians shows they require a confidence‑based escalation mechanism, prefer different handling of uncertainty types, and will only accept liability when transparency allows informed decision‑making.
By Eileanor LaRocco, Sarah Tan, Adarsh Subbaswamy, Anne Andrews, Andrew Taylor, Cree Gaskin, Chirag Agarwal
arXiv:2608. 03028v1 Announce Type: new Abstract: Applying a valid medication-safety rule when its patient-specific conditions are not met can produce an incorrect decision.
By Zhitian Hou, Yuhang Liu, Pengkai Wang, Zeyu Liu, Guanghao Zhu, Zheng Liu, Shuo Cai, Congkai Xie, Zhijie Sang, Kun Zeng, Hongxia Yang
arXiv:2608.22899v1 Announce Type: new
Abstract: Unlike static medical question answering, long-horizon diagnosis captures the sequential nature of clinical practice: evidence is progressively acquire...
By Xiwei Dai, Zijie Meng, Zhiting Fan, Yixuan Tang, Ziru Niu, Zuozhu Liu
arXiv:2606. 16149v3 Announce Type: replace Abstract: Rare disease diagnosis depends on expert reasoning that is scarce and difficult to transfer; off-the-shelf large language models (LLMs) rank the correct disease first in only 35.
By Minh-Ha Nguyen, Erica Gray, Bryce A. Schuler, Kevin W. Byram, Chih-Ting Yang, Fan Ma, Hua Xu, Wu-Chen Su, Chao Yan, Wei-Qi Wei, Adam Wright, Lisa Bastarache, Josh Peterson, Lingyao Li, Siyuan Ma, Undiagnosed Diseases Network, Rizwan Hamid, Thomas A. Cassini, Cathy Shyr
arXiv:2607. 17508v1 Announce Type: cross Abstract: We introduce Retrieval-Augmented Interpretable Learning (RAIL), a probabilistic meta-learning framework for zero-shot generation of task-specific interpretable models that synthesizes coefficient-space structure from natural-language task descriptions and a memory of previously learned task-specific predictors.
By Sazan Mahbub, Caleb Ellington, Zhiyuan Li, Yixin Yang, Souvik Kundu, Ben Lengerich, Eric P. Xing