arXiv Computation and Language

Accounting for Irregular State Transitions through Belief Estimation in Online Medical Consultation

The paper introduces PRISM, a framework that separates belief estimation from action selection to handle irregular state transitions in online medical consultations. By maintaining a posterior belief over consultation states, PRISM improves clinical decision accuracy by 22.40 percentage points and response quality by 5.51 BERTScore_F1 points compared to leading LLMs and clinical agents. Ablation studies confirm that oracle state information further enhances response quality across baselines.

arXiv Computation and Language
Sep 1

MedConceal: A Benchmark for Clinical Hidden-Concern Reasoning Under Partial Observability

MedConceal is a new benchmark for evaluating medical dialogue systems on hidden‑concern reasoning under partial observability. It features 300 curated cases and 600 clinician‑LLM interactions, using an interactive patient simulator that hides latent concerns and tracks their revelation and resolution through theory‑grounded communication signals. The benchmark assesses both confirmation (surfacing hidden concerns) and intervention (addressing the primary concern), revealing that current models excel on different metrics while human clinicians still outperform them on intervention success.

By Yikun Han, Joey Chan, Jingyuan Chen, Mengting Ai, Simo Du, Yue Guo
arXiv AI
Sep 28

ConsultMind:Towards Automated Diagnostic Consultation via Uncertainty-Aware Reasoning

ConsultMind is an uncertainty‑aware framework that automates diagnostic consultation by updating disorder posteriors after each patient response and using posterior uncertainty to guide inquiry and diagnosis. It builds on AutoDisym, a pipeline that constructs a Disorder–Symptom Bayesian Network (DSBN) from diagnostic knowledge and clinical narratives. Across psychiatry, respiratory medicine, fever clinics, and public datasets, AutoDisym produces high‑quality DSBNs and ConsultMind improves diagnostic accuracy and explanation quality, achieving up to 22.15‑point gains in Top‑1 accuracy and 37.89‑point gains in Top‑3 accuracy.

By Xiao Sun, Yuming Yang, Yun Chen, Jiang Zhong, Junnan Zhu, Xinyi Jiang, Haoyang Zeng, Ruirui Chen, Yining Wang, Xinyu Zhou, Rong Tang, Kaiwen Wei
arXiv AI
Oct 15

Reinforcement Learning In Partially Verifiable Environments for Colon Cancer Treatment Planning

arXiv:2610.17426v1 Announce Type: cross Abstract: Clinical decision-making is a sequential process of information collection, clinical inference, and forecasting under partial observability, often wi...

By Li-Ching Chen, Andr\'es Franco Valiente, Yuta Ishiyama, Zachary R. Chalmers, William Chen, Kelsey Natsuhara, Taema Brinjikji, Madhumita Sushil, Travis Zack, Julian C. Hong
arXiv AI
Jul 28

OpenAIs HealthBench in Action: Evaluating an LLM-Based Medical Assistant on Realistic Clinical Queries

arXiv:2509. 02594v3 Announce Type: replace-cross Abstract: Evaluating large language models (LLMs) on their ability to generate high-quality, accurate, situationally aware answers to clinical questions requires going beyond conventional benchmarks to assess how these systems behave in complex, high-stakes clinical scenarios.

By Sandhanakrishnan Ravichandran, Shivesh Kumar, Rogerio Corga Da Silva, Miguel Romano, Reinhard Berkels, Michiel van der Heijden, Olivier Fail, Valentine Emmanuel Gnanapragasam
arXiv Computation and Language
Sep 1

GPAgentBench-2K: Benchmarking Large Language Model Agents in Complex Clinical Action Space

GPAgentBench-2K is a new benchmark that evaluates large language model agents in primary‑care clinical decision‑making using a constrained Markov Decision Process (CMDP). It is built from expert‑validated records of real GP encounters and includes six foundational clinical actions, a workflow prior, and safety‑informed abstention as an outcome. Testing 16 state‑of‑the‑art LLMs shows that performance drops as the action space grows and that even the best models violate safety constraints in more than half of high‑risk cases, highlighting a gap between clinical quality and safety.

By Boqi Chen, Xudong Liu, Yunke Ao, Heejin Do, Jianing Qiu
arXiv Computation and Language
Oct 5

Understanding Clinical Cognitive Dialogues Using Large Language Models

The paper introduces a de‑identified corpus of 33 in‑person cognitive assessment conversations, comprising 8,250 utterances annotated for three speaker roles and 56 dialogue acts. The authors benchmark large language models on fine‑grained dialogue‑act classification and next‑patient‑utterance generation, finding that instruction tuning and reasoning‑aware fine‑tuning improve performance but that models still struggle with closely related dialogue acts. The corpus and benchmark are presented as tools to measure interaction structure in cognitive assessments and to support future research on conversational markers, clinician education, and validated simulated patients.

By Vishalakshi Arumugam, Dan Schumacher, Veronica Rammouz, Erfan Nourbakhsh, Enrique Gonzalez Guerrero, Jeremy Davis, Anthony Rios
arXiv Computation and Language
Sep 11

Towards Reliable Medical LLMs: Benchmarking and Enhancing Confidence Estimation of Large Language Models in Medical Consultation

The paper introduces the first benchmark for evaluating confidence estimation in large language models during multi‑turn medical consultations, combining three types of medical data and an information sufficiency gradient to capture how confidence and correctness evolve as evidence accumulates. Experiments with 27 methods reveal that token‑level and consistency‑level confidence approaches are limited by medical data, and that medical reasoning must be judged on both diagnostic accuracy and information completeness. Building on these findings, the authors propose MedConf, a retrieval‑augmented, linguistically grounded self‑assessment framework that aligns patient information with supporting, missing, and contradictory relations, producing interpretable confidence estimates that outperform existing methods across multiple datasets and LLMs.

By Zhiyao Ren, Yibing Zhan, Siyuan Liang, Guozheng Ma, Baosheng Yu, Dacheng Tao