The paper introduces SlideTIM, a transductive few‑shot classification method tailored for whole‑slide images (WSIs). SlideTIM extends the LC‑TIM approach by adding a spatial‑latent regularizer and a class‑distribution prior, ensuring that spatially and semantically similar patches receive consistent predictions and that predicted class proportions are calibrated. Experiments on four histology datasets show that SlideTIM outperforms existing TIM variants, boosting macro‑F1 scores by up to 8.1 percentage points over the best baseline and 19.4 percentage points over zero‑shot predictions at one shot.
arXiv:2608.30420v1 Announce Type: cross Abstract: Automating the analysis of whole-slide images has high clinical value, since characterizing cancers requires examining them in detail. Such analysis...
LanGuSTE is a patch‑selection framework for whole slide image analysis that uses vision‑language models and large language model knowledge. It introduces Cross‑Scale Visual Prompt Tuning to align low‑resolution and high‑resolution patches, and a coarse‑to‑fine selection module that encodes only informative high‑resolution patches. Experiments show LanGuSTE cuts overall processing time to about one‑third of the baseline while matching or surpassing diagnostic performance of exhaustive and state‑of‑the‑art methods.
The paper introduces a pipeline that uses publicly available whole slide image foundation models (FMs) to automatically triage slides by ranking them based on zero‑shot classification predictions. This approach accurately identifies slides containing the most tumor, achieving top‑2 ranking for patients with up to 43 slides across multiple datasets. The study also proposes a ranked evaluation framework to benchmark FM performance in slide triage.
arXiv:2609.00396v1 Announce Type: new Abstract: Histopathological whole slide images (WSIs) are central to cancer diagnosis, but their gigapixel scale, tissue heterogeneity, weak slide-level supervis...
The paper introduces FFM-CP, a framework that fuses multiple pathology vision‑language foundation models for few‑shot learning. It aligns heterogeneous representations with an Orthogonal Procrustes transformation, then uses a unified graph to refine support‑image features and class prototypes across backbones. Experiments on six histopathology datasets show that FFM‑CP outperforms the best single adapted model in 50 of 54 few‑shot comparisons.
arXiv:2609.24894v1 Announce Type: cross Abstract: Whole-slide pathology images (WSIs) contain gigapixel-scale visual content, creating a major scalability challenge for slide-level multimodal large l...
The study investigates whether pathology foundation models (PFMs) carry center-related biases into whole-slide image (WSI) classification. By training models with increasing class-center correlations and evaluating six PFMs across four datasets and two MIL aggregators, the authors introduce the Area Under the Cramér's V Curve (AUCC) to measure both accuracy and degradation due to spurious correlations. Results reveal that center information propagates to WSI predictions, with robustness varying by PFM and MIL strategy, and that ComBat harmonization does not consistently improve robustness.
Whole slide image (WSI) classification is an evidence-driven task, where diagnostic cues are often sparse, spatially organized, and class-dependent. Existing MIL and vision-language methods aggregate a large pool of patch features into a single global slide representation.
arXiv:2605. 30716v2 Announce Type: replace-cross Abstract: Generating clinically useful pathology reports for pathology cases from whole-slide images (WSIs) is challenging due to gigapixel resolution, long visual-token sequences, and the complexity of case-level reasoning, where a single case may contain multiple WSIs with heterogeneous tissues and ambiguous findings.
The paper introduces Spatial‑FAD, a few‑shot medical anomaly detection framework that fuses Vision‑Language Model (CLIP) semantics with spatial priors from Vision Foundation Models (DINO). A VFM‑enhanced adapter injects structural affinity into CLIP features, while a sliding‑window aggregation produces high‑resolution embeddings for finer lesion localization. Prototype‑enhanced support memory further improves efficiency and performance, yielding significant gains on Liver CT, Retinal OCT, and Brain MRI datasets, notably an 11.4% Dice improvement in 4‑shot scenarios.
SlideBank is a training‑free framework that turns each whole‑slide image into a persistent, concept‑indexed evidence bank. It performs coarse‑to‑fine exploration to locate informative regions and multi‑scale views, converts them into explicit morphological observations, and anchors pathology signals to the supporting patches and slide coordinates. During inference, questions are routed to relevant signals and evidence scales, and a confidence‑based cross‑level consensus integrates global, regional, and patch evidence, achieving high accuracy on WSI‑VQA and SlideBench‑BCNB while enabling consistent re‑phrasing and reduced inference cost.
The paper introduces Spectral Transductive Refinement (STR), a training‑free method that refines class prototypes at test time using the geometry of a joint k‑nearest‑neighbour graph and a normalized‑Laplacian spectral coordinate system. STR operates solely on frozen visual embeddings, iteratively updating pseudo‑labelled queries to improve one‑shot and few‑shot classification under domain shift. Experiments on ResNet‑18 and ResNet‑10 backbones show STR outperforms single‑prototype baselines and rivals meta‑trained cross‑domain few‑shot methods, achieving the best 1‑shot average across eight target domains.