Cardiologists interpret electrocardiograms by localizing waveform components, measuring rhythm and interval patterns, and translating these structured observations into diagnostic evidence. Whether this expert reading process can serve as an effective prior for ECG agents remains unclear.
arXiv:2608. 05893v1 Announce Type: new Abstract: Electrocardiography (ECG) is one of the most widely used non-invasive tools for diagnosing cardiovascular disease, but transforming multi-lead ECG recordings into reliable clinical reports remains challenging.
By Akanta Das, Tasinul Islam Ahon, Ahmed Mahir Sultan Rumi, Md Mahbubur Rahman, Tausif Amim Shadly, Tanzima Hashem
arXiv:2607. 16323v1 Announce Type: cross Abstract: Electrocardiography (ECG) is an inexpensive, standard-of-care test for cardiac symptoms, but front-line triage often lacks immediate access to definitive imaging such as echocardiography (ECHO) or cardiac magnetic resonance (CMR).
By Alexander Selivanov, Friederike Jungmann, Jan Kehrer, Karl-Ludwig Laugwitz, Eimo Martens, Daniel Rueckert
arXiv:2605. 29977v2 Announce Type: replace-cross Abstract: High-fidelity ECG interpretation is increasingly reliant on massive foundation models, yet their deployment in clinical edge-care remains hindered by extreme computational demands.
By Dang Nguyen Hong, Nhi Ngoc-Yen Nguyen, Huy-Hieu Pham
arXiv:2607. 24035v1 Announce Type: cross Abstract: Explainable AI (XAI) is used to assess whether artificial intelligence models rely on meaningful patterns, yet explanations that appear plausible for individual predictions may systematically misrepresent model behavior.
By Nils Gumpfer, Michael Guckert, Samuel Sossalla, Birgit A{\ss}mus, Jennifer Hannig
ECGQuest is a new benchmark that evaluates language models on the contextual knowledge required for electrocardiogram interpretation, featuring 10,904 True/False questions derived from 23 ECG references and 2003‑2025 Computing in Cardiology proceedings. The study tested 23 commercial and open‑source models, finding that zero‑shot accuracy ranged from 49.5% to 74.4% and that fine‑tuning with Low‑Rank Adaptation improved all open‑source models by 6.5–14.1%, with the best fine‑tuned model achieving 76.3% accuracy and a five‑model ensemble reaching 78.5%. ECGQuest demonstrates that parameter‑efficient fine‑tuning can enable smaller models to compete with larger commercial ones on ECG‑specific tasks.
By Mohammadsina Hassannia, Matthew A. Reyna, Reza Sameni
FOCAL is a framework that aligns fine-grained ECG waveform segments with specific report tags using Optimal Transport, addressing the lack of localized representation in prior methods. It introduces a semantic similarity matrix to mitigate false negatives when reports share diagnoses, and a coarse‑to‑fine enrichment pipeline that employs Large Language Models to recover missing waveform semantics while filtering hallucinations. Experiments on six datasets show FOCAL achieves state‑of‑the‑art zero‑shot prediction and linear probing performance.
By Haitao Li, Che Liu, Zhengyao Ding, Ziyi Liu, Wenqi Shao, Zhengxing Huang
arXiv:2609.21755v1 Announce Type: new
Abstract: Emergency department (ED) decision-making relies on heterogeneous clinical information, including patient history, vital signs, laboratory results, and...
By Jinning Liang, Mingcheng Zhu, Tingting Zhu
BEAT-Net is a supervised biomimetic framework for ECG diagnosis that incorporates QRS-centered tokenization and a hierarchical architecture mirroring a cardiologist’s workflow. It processes heartbeat sequences through morphological, spatial, temporal, and transformer-based stages, achieving an AUC of 0.924 on large benchmarks while using only 0.7 million parameters. The model outperforms the 39.5‑million‑parameter HeartLang foundation model on morphological form classification and demonstrates superior cross‑dataset generalization with only 35% of the training data.
By Runze Ma, Haonan Lyu, Shunbo Jia, Qiang Yang, Muzi Xu, Jiaqi Zhang, Zihe Luo, Caizhi Liao
The study demonstrates that contrastive pre‑training of ECG representations using cardiac magnetic resonance (CMR) imaging data can enhance ECG‑based detection of Chagas disease. By aligning an ECG encoder with a CMR embedding space from 63,193 paired UK Biobank examinations, the authors achieved higher AUROC and sensitivity metrics on CODE‑15%, SaMi‑Trop, and PhysioNet/CinC 2025 Challenge datasets compared to an unaligned baseline. The approach shows that imaging‑supervised ECG representations generalize across different populations and resource‑constrained settings.
By Laura Alvarez-Florez, Daniel Uyterlinde, Samuel Ruip\'erez-Campillo, Lukas P. A. Arts, Folkert W. Asselbergs, Fleur V. Y. Tjong
arXiv:2607. 20814v1 Announce Type: new Abstract: The electrocardiogram (ECG) is a cornerstone of cardiac as- sessment, yet clinical deployment of deep learning models remains con- strained by limited interpretability and the hallucination risk of large language models (LLMs).
By Hai-Nam Duy Vuong, Duy-Anh Bui, Trong-Nghia Nguyen, Kim-Ngan Thi Nguyen, Trang Mai Xuan, Tien-Cuong Nguyen, Van-Dem Pham, Thien Van Luong
arXiv:2607. 07683v1 Announce Type: new Abstract: Electrocardiography (ECG) is one of the most widely used tests for diagnosing cardiovascular disease.
By Shreyasvi Natraj, Cyrus Achtari, Felice Gragnano, Andrea Milzi, Marco Valgimigli, Diego Paez-Granados