arXiv:2610.34871v1 Announce Type: new
Abstract: Objective: The rapid advancement of large language models (LLMs) in healthcare has opened new possibilities for AI-assisted clinical decision-making; h...
By Asad Gohar, Md Ariful Islam Mozumder, Moon-Il Joo, Hee-Cheol Kim
arXiv:2605. 18937v2 Announce Type: replace Abstract: Patient-managed Personal Health Records (PHRs) promises to empower patients to better understand their health; but information in the record is complex, potentially hindering insights.
By Rory Sayres, Kejia Chen, Ayush Jain, Matthew Thompson, Jonathan Richina, Xiang Yin, Jimmy Hu, Fan Zhang, Bob Lou, Mike Sanchez, Ines Mezerreg, Meredith Schreier, Hamsa Subramaniam, I-Ching Lee, Yugang Jia, Daniel Mcduff, Yossi Matias, Avinatan Hassidim, Dale Webster, Yun Liu, Jackie Barr, Quang Duong
The paper explores how Large Language Models (LLMs) such as GPT-4o-mini, Gemini-1.5-pro, and LLaMA can be used to automatically simplify complex medical texts into plain language, a process known as Plain Language Adaptation (PLA). It evaluates different prompting strategies, fine‑tunes models with QLoRA, and incorporates Mixture‑of‑Agents (MoA) techniques to improve adaptability and robustness. The results show that LLM‑driven PLA effectively makes healthcare information more comprehensible while preserving essential content.
By Ting-Wei Chang, Hen-Hsen Huang, Hsin-Hsi Chen
arXiv:2609.38543v1 Announce Type: new
Abstract: Constantly evolving real-world knowledge necessitates models to be updated continuously. Especially in medicine, as clinical evidence changes over time...
By Lukas Thede, Yash Kumar Atri, David Chen, Danielle Bitterman, Matthias Bethge, Tom Hartvigsen, Zeynep Akata
The paper surveys open, non‑proprietary large language models (LLMs) and AI foundation models (AIFMs) for clinical use, presenting a taxonomy of current state‑of‑the‑art models. It empirically tests open‑weight LLMs on a personalized‑prescription task, finding that they match or surpass a proprietary baseline in overall suitability accuracy, especially when combined with Retrieval‑Augmented Generation (RAG). A subjective evaluation by blinded raters shows mixed effects of RAG on perceived suitability across multiple dimensions, and the authors discuss ethical risks and the need for responsible deployment.
By Mahdi Alkaeed, Sofiat Abioye, Adnan Qayyum, Yosra Magdi Mekki, Ilhem Berrou, Mohamed Abdallah, Ala Al-Fuqaha, Muhammad Bilal, Junaid Qadir
arXiv:2608. 19875v1 Announce Type: cross Abstract: Patients often submit short, underspecified queries to healthcare chatbots that lack the patient-specific information needed to determine an appropriate response.
By Mahyar Abbasian, Saba A. Farahani, Arshia Ilaty, Hung Cao, Ramesh Jain, Amir M. Rahmani
MIRA is a bilingual benchmark that evaluates whether large language models (LLMs) provide consistent medical information across different user phrasings, languages, and health literacy levels. It contains 4,320 prompts derived from 60 medically reviewed low‑risk health questions and reveals that models tend to omit key information and offer fewer concrete next steps when responding to low health‑literacy signals, a phenomenon termed Differential Information Dilution (DID). A knowledge‑guided mitigation prompt can reduce this dilution for most models, notably improving Claude and Qwen.
By Mengyu Xu, Qiaoxin Yang, Qianqian Wang, Xiwei Dai, Weiyi Wu, Chongyang Gao
arXiv:2611.00460v1 Announce Type: cross
Abstract: Large language models (LLMs) now answer medical exam questions at or above expert level, but it is unclear whether such scores reflect clinical compe...
By Navapat Nananukul, Mayank Kejriwal
arXiv:2609.22161v1 Announce Type: cross
Abstract: Medical large language models are commonly trained on mixtures of didactic data (e.g., textbooks) and clinical data (e.g., patient records), yet how...
By Yuzheng Fan, Haochun Wang, Sendong Zhao, Xiao Han, Ming Ma, Bing Qin
arXiv:2607. 06641v1 Announce Type: cross Abstract: Large language models (LLMs) achieve promising results on medical question answering benchmarks, yet their use in public health is constrained by hallucinations and the rapid evolution of official guidance.
By Felix Feldman, Joshua Harris, Timothy Laurence, Leo Loman, Ollie Higgins, Fan Grayson, Poonam Soma, Bethany Pace-Bonello, Michael Borowitz, Toby Nonnenmacher
ClinAgent is a conversational system that uses a ReAct-based LLM agent to retrieve and synthesize clinical trial information from multiple sources such as ClinicalTrials.gov, PubMed, and a local dataset. The agent iteratively reasons over user queries, selects appropriate tools, and refines its actions to provide grounded, up-to-date responses in natural language across multi-turn interactions. Evaluation across three phases shows that DeepSeek (thinking mode) excels in planning quality while Gemini 3.0 Flash delivers the highest overall performance and expert ratings, demonstrating the promise of agentic AI for improving clinical trial data access.
By Antonino Vaccarella, Riccardo Cantini, Domenico Talia, Paolo Trunfio, Marianna Talia, Rosamaria Lappano, Marcello Maggiolini
The paper examines how Retrieval-Augmented Generation (RAG) and Named Entity Recognition (NER) affect the quality of lay summaries of radiology reports. Using a framework that extracts clinically relevant findings via NER and grounds them with RAG, the authors evaluate few‑shot and fine‑tuned versions of Qwen and BioBART. Results show that NER consistently improves readability and overall quality, RAG alone offers no benefit and can introduce hallucinations, and the best performance comes from fine‑tuned BioBART with NER.
By Egecan \c{C}elik Evgin, \.Ilknur Karadeniz, Olcay Taner Y{\i}ld{\i}z