Breast cancer remains a leading cause of cancer-related mortality among women. Its clinical management requires multimodal reasoning across a clinical workflow that spans \textit{screening}, \textit{diagnosis} and \textit{treatment planning}, where each stage involves distinct imaging modalities, task objectives, and reasoning patterns.
arXiv:2511.22232v2 Announce Type: replace-cross Abstract: Multimodal large language models (MLLMs) are increasingly capable in medical imaging, yet most focus on single-image settings. Clinical inter...
Lingshu is a medical‑specialized multimodal large language model that addresses key limitations of existing medical MLLMs, such as narrow knowledge coverage, hallucinations, and weak reasoning. The authors curate a comprehensive dataset combining medical imaging, texts, and general‑domain data, then train Lingshu in multiple stages to embed medical expertise and improve task performance. They also introduce MedEvalKit, a unified evaluation framework, and demonstrate that Lingshu outperforms current open‑source multimodal models on multimodal QA, text‑based QA, and medical report generation.
The paper introduces MedREAL, a unified framework that aligns linguistic reasoning with spatial grounding for medical visual question answering and segmentation. MedREAL employs Seg Anchored Reasoning Pooling (SARP) to extract semantic evidence from segmentation tokens and a Reasoning-to-Visual (R2V) fusion mechanism to integrate these features into a segmentation pipeline. Using the newly created MedRAVS-13K dataset, MedREAL achieves superior performance, reporting 68.49% gIoU and 70.47% cIoU, and generates evidence masks that consistently match textual diagnoses.
arXiv:2508. 16129v3 Announce Type: replace Abstract: Multimodal large language models (MLLMs) have recently demonstrated remarkable reasoning abilities with reinforcement learning paradigm.
arXiv:2606. 28556v1 Announce Type: new Abstract: Recent advances in large language models and vision-language models have enabled reasoning over multimodal data, offering opportunities for clinical applications such as decision support and triaging.
arXiv:2409.16183v2 Announce Type: replace Abstract: Radiology is a vital and complex component of modern clinical workflow and covers many tasks. Recently, vision-language (VL) foundation models in m...
The paper introduces the Boot-and-Feedback (BooF) framework, which facilitates collaboration between multimodal large language models (MLLMs) and expert vision models for breast ultrasound (BUS) diagnosis. In the Boot Stage, the MLLM is guided by the BI-RADS lexicon and preliminary expert predictions to generate reliable textual descriptions, while the Feedback Stage fuses these descriptions with visual features using an Attention-Gated Cross-Modality Fusion Module, allowing the expert model to incorporate textual insights and filter out noise. Experiments on multiple BUS datasets show that BooF improves both diagnostic accuracy and interpretability compared to existing methods.
arXiv:2606. 12169v1 Announce Type: cross Abstract: High-stakes clinical use of large vision-language models (LVLMs) requires reasoning that is grounded in visual evidence and clinical knowledge, not just correct final answers.
arXiv:2607. 25933v1 Announce Type: cross Abstract: Clinical diagnostic evaluation should not only assess whether models can provide correct diagnoses, but also reflect the realities of clinical practice, including progressive disclosure of multimodal information, dynamic updating of diagnostic hypotheses, and continuous refinement of clinical reasoning.
arXiv:2603.00842v2 Announce Type: replace Abstract: Biomedical multimodal assistants have the potential to unify radiology, pathology, and clinical-text reasoning, yet a critical deployment gap remai...
Breast ultrasound (BUS) is widely used for breast cancer diagnosis yet remains operator-dependent. While deep learning shows promise, ensuring diagnostic reliability and interpretability is challengin...
arXiv:2603.02790v2 Announce Type: replace Abstract: Foundation models are changing the way we develop medical artificial intelligence. By learning broadly generalizable features across diverse data m...