arXiv Machine Learning

A multimodal large language model for evidence-based autism spectrum disorder screening

arXiv AI
Sep 28

UniAR: A Unified Framework for Autism Recognition Enhanced by Multi-View Prompt Learning

UniAR is a unified framework that improves autism spectrum disorder (ASD) recognition by using multi-granularity prompt learning and a large multimodal model to generate diagnostic descriptions at word, phrase, and sentence levels. It aligns these semantic representations with visual evidence through a Mixture-of-Experts-based Multi-Scale Alignment Module, enabling robust ASD detection across heterogeneous data types. Experiments on four brain MRI and facial expression benchmarks show that UniAR outperforms state‑of‑the‑art methods, achieving 75.9% accuracy on MRI and 91.6% on facial benchmarks, with gains of 1.5 and 1.2 percentage points respectively.

By Lei Xin, Zeheng Wang, Jiayin Zhu, Shihong Huang, Fanhu Zeng, Changjiang Jiang, Dengbo He, Yutao Yue, Zhenglun Kong
arXiv AI
Aug 20

A systematic review of machine learning techniques to address diagnosis and treatment of autism: challenges and opportunities

The article reviews 55 machine‑learning studies on autism spectrum disorder (ASD) published between 2017 and 2023, focusing on how ML can aid early diagnosis and treatment. It finds that supervised learning dominates current research, while deep learning is gaining traction as data volumes grow. The review highlights the need for models that fuse complex data—such as genetic, clinical, wearable, and biometric sources—to improve diagnostic accuracy and enable continuous, non‑intrusive monitoring.

By Rafael Mu\~noz-Terol, Jes\'us Peral, Sandra Amador, David Gil
arXiv Computation and Language
Sep 23

SpecialEduBench: Benchmarking Vision-Language Models on Knowledge, Skill, and Attitude in Language Intervention for Autistic Children

SpecialEduBench is a new benchmark for vision‑language models that evaluates their pedagogical competence in language intervention for autistic children across knowledge, skill, and attitude dimensions. It contains 4,537 knowledge items, 200 skill items, and 68 attitude items derived from recorded interventions, with 192 response cells for attitude items that combine pressure and monitoring. Eight leading vision‑language models were tested, none achieving full performance, especially in honesty cells, indicating that current models still struggle with situated teaching tasks.

By Jihoi Na, Taeyeong Kim, Sungjune Kong, Jaemin Jung, Min Joung Park, Kyungtae Joo, Ahhyun Kim, Shim Jaechang, Sooyoung Joo, Dongjin Ka, SeJoong Kim, Jimin Kim, HyunJin Jung, Unggi Lee
arXiv AI
Sep 1

AOI-Net: Structural Face AOI-Guided Eye-Gaze Track Representation Learning for Autism Spectrum Disorder Detection

AOI-Net introduces a structural face AOI-guided Eye‑Gaze Track Network that jointly models short‑term temporal dynamics and AOI‑level structural organization for Autism Spectrum Disorder detection. The network uses a gating mechanism to adaptively combine complementary representations and incorporates class‑distribution‑aware learning to address the imbalance between ASD and typically developing participants. Experiments on a large clinical eye‑tracking database with over 1,300 participants demonstrate that AOI‑Net outperforms state‑of‑the‑art methods and offers interpretable gaze‑behavior modeling for scalable AI‑driven ASD screening.

By Zhanpei Huang, Binbin Sun, Jialiang Chen, Yiou Wang, Taochen Chen, Yuzhu Ji, Yiqun Zhang, Yiu-Ming Cheung
arXiv Computation and Language
Sep 28

Why Alzheimer's Speech Screening Fails to Generalize: Bridging the Deployment Gap via Cross-Corpus Evidence Anchoring

The paper examines why speech‑based screening for Alzheimer’s disease fails to generalize across different languages, tasks, and recording protocols. Using a leave‑one‑corpus‑out evaluation on four datasets, it finds that 59 of 70 interpretable speech features show conflicting patterns between healthy controls and cognitive risk groups, with pause, silence, and speech rate being highly protocol‑sensitive. The authors propose a fusion method that combines XLM‑R text baseline scores with evidence anchors, improving mean speaker AUC to 0.785 and worst‑case AUC to 0.615, and emphasize the importance of auditing feature transferability and reporting worst‑case domain robustness.

By Zijian Lu, Sizhe Liu, Yin Zhang, Jixuan Deng, Xinrong Lin, Xinchen Yuan, Chicheng Jin, Yiping Zuo, Yuanchao Li
arXiv AI
Aug 11

Temporal Generalization in fNIRS-Based Autism Classification: A Cross-Time-Window Transfer Benchmark

arXiv:2608. 07567v1 Announce Type: cross Abstract: Functional near-infrared spectroscopy (fNIRS) is a promising modality for autism spectrum disorder (ASD) classification, yet existing approaches assume temporally aligned evaluation.

By Marios Petrov, Sahana Vinayak, Targol Bakhtiarvand, Moses Smith Guddah, Adham Atyabi, Frederick Shic, Kevin A. Pelphrey