arXiv:2606. 12006v1 Announce Type: cross Abstract: Predicting time-to-event outcomes such as mortality is a fundamental task in clinical decision-making, commonly addressed through survival analysis.
By Minh-Khoi Pham, Luca Cotugno, Alina Sirbu, Tai Tan Mai, Martin Crane, Marija Bezbradica
arXiv:2610.03693v1 Announce Type: new
Abstract: Scarcity of labeled data limits development of deep learning biomarkers in oncology. We develop a two-stage AI model predicting pathological complete r...
By Jungkyu Park, Dhruva Biswas, Joseph Cappadona, Cerise Tang, Ken G. Zeng, Bartosz Machura, Chuwen Liu, Paolo Tarantino, Coral Omene, Francisco J. Esteva, Rohit Bhargava, Marcin Braun, Kamila Pa\'zdzierz, Jakub Czerwi\'nski, Hanna Roma\'nska-Knight, Albert Grinshpun, Bareket Daniel, Michele Buchinger, Frederick Howard, Piotr Wysocki, Brie Chun, Freya Schnabel, Rich Caruana, Jan Witowski, Krzysztof J. Geras
arXiv:2601. 22259v2 Announce Type: replace Abstract: While tabular foundation models have achieved remarkable success in classification and regression, adapting them to model time-to-event outcomes for survival analysis is non-trivial due to right-censoring, where data observations may end before the event of interest occurs.
By Da In Kim, Wei Siang Lai, Kelly W. Zhang
arXiv:2512. 17678v2 Announce Type: replace-cross Abstract: Selecting compact and informative gene subsets from single-cell transcriptomic data is essential for biomarker discovery, improving interpretability, and cost-effective profiling.
By Daphn\'e Chopard, Jorge da Silva Gon\c{c}alves, Irene Cannistraci, Thomas M. Sutter, Julia E. Vogt
arXiv:2606. 31126v1 Announce Type: new Abstract: Predicting biomolecular properties from limited labeled data is a central bottleneck in protein engineering and small-molecule design.
By Davy Guan, Lu Zhang, Asiri Wijesinghe, Allen Zhu, He Zhao, Helen Power, F. Hafna Ahmed, Andrew Warden, Cheng Soon Ong, Daniel M. Steinberg
CellMSA introduces a novel single‑cell representation learning framework that leverages a multiple‑sequence‑alignment‑inspired context model. For each target cell, it retrieves relevant cells across batches and related cell types, summarizing cross‑cell patterns into a context‑dependent gene‑pair representation that is fed into a pair‑aware encoder. Pretraining on a massive human single‑cell corpus (≈109 million cells) and subsequent benchmarks demonstrate consistent performance gains over existing methods.
By Suyuan Zhao, Minghao Liu, Yizhen Luo, Zaiqing Nie
arXiv:2606. 04564v1 Announce Type: new Abstract: Tabular foundation models (TFMs) have made rapid progress in standard classification and regression, but time-to-event survival prediction tasks have remained largely untouched.
By Samuel B\"ohm (Institute of Epidemiology and Prevention, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany), Lennart Purucker (Department of Computer Science, University of Freiburg, Freiburg, Germany, PriorLabs, Freiburg, Germany), Frank Hutter (Department of Computer Science, University of Freiburg, Freiburg, Germany, PriorLabs, Freiburg, Germany), Pascal Schlosser (Institute of Epidemiology and Prevention, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany, Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, US, CIBSS - Centre for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany)
TabICLv2 is a new state‑of‑the‑art tabular foundation model that outperforms existing methods on regression and classification tasks. It relies on a synthetic data generation engine for diverse pretraining, architectural innovations such as a scalable softmax attention, and optimized training protocols that replace AdamW with the Muon optimizer. On the TabArena and TALENT benchmarks, TabICLv2 surpasses the current best model, RealTabPFN‑2.5, without any tuning, while also being faster and capable of handling million‑scale datasets with limited GPU memory.
By Jingang Qu, David Holzm\"uller, Ga\"el Varoquaux, Marine Le Morvan
The paper explores how to adapt tabular foundation models (TabFMs) for censored time‑to‑event prediction by linking them with CoxPH and DeepHit and revising training procedures. It evaluates zero‑shot, classification‑based fine‑tuning, and survival‑head adaptations across 74 single‑risk and 4 competing‑risk datasets, finding that zero‑shot works best on small datasets while supervised adaptation excels as data grows. The study shows that the choice of adaptation interface and data regime critically influences TabFM transfer performance.
By Minh-Khoi Pham, Luca Cotugno, Dan Cernei, Alina Sirbu, Stefano Masi, Giuseppe Prencipe, Alessandro Pingitore, Patrizia Landi, Working Group on Uric Acid, Cardiovascular Risk of the Italian Society of Hypertension, Tai Tan Mai, Martin Crane, Marija Bezbradica
arXiv:2510. 17532v2 Announce Type: replace-cross Abstract: Predicting cancer treatment outcomes requires models that are both accurate and interpretable, particularly in the presence of heterogeneous clinical data.
By Raghu Vamshi Hemadri, Geetha Krishna Guruju, Kristi Topollai, Anna Ewa Choromanska
The paper introduces the General Demographic Pre-trained (GDP) model, a lightweight foundation model that learns representations from the two most common clinical attributes—age and sex. By optimizing encoding and visit‑reordering strategies, GDP embeddings are shown to improve predictive performance when concatenated with raw features across various disease and geographic cohorts. The model outperforms several state‑of‑the‑art tabular foundation models and tree‑based algorithms, demonstrating that enriched demographic embeddings can enhance classification tasks while remaining fully compatible with standard classifiers.
By Li-Chin Chen, Ji-Tian Sheu, Yuh-Jue Chuang
arXiv:2410. 00945v2 Announce Type: replace-cross Abstract: Gene-expression profiling is widely used in research and central to many areas of precision oncology, but remains costly and not universally accessible.
By Fredrik K. Gustafsson, Constance Boissin, Johan Vallon-Christersson, Mattias Rantalainen