arXiv Machine Learning
Jun 24

Federated Survival Analysis in Healthcare: A Multi-Model Evaluation on Cross-Institutional Heterogeneous Breast Cancer Data

arXiv:2606. 23871v1 Announce Type: new Abstract: Survival analysis is central to clinical decision-making, yet reliable time-to-event models require large, diverse cohorts that are rarely available at a single institution, while privacy regulations restrict the centralization of patient data.

By Natalia Moreno-Blasco, Anusha Ihalapathirana, Pekka Siirtola, Miguel Fernandez-de-Retana
arXiv Machine Learning
4d ago

Graph-Enhanced Disease Trajectory Discovery and Temporal Endpoint Forecasting from Longitudinal Electronic Health Records

The study introduces a graph‑enhanced framework for discovering disease trajectories and forecasting temporal endpoints using longitudinal EHR data from MIMIC‑IV v3.1. It constructs patient‑specific motifs from consecutive admissions, applies a time‑aware Transformer to select up to 24 motifs per endpoint, and reports modest improvements in micro‑AUPRC and event‑time MAE, with larger gains for events occurring after 730 days. The authors also explore branching‑motif conditioning and GNN‑based edge repair, finding that motifs mainly provide long‑range timing support rather than superior endpoint discrimination or survival prediction.

By Jin-Jia Zheng, Vincent S. Tseng
arXiv AI
Jul 23

SynPre-FL: Synthetic data-driven pretraining integrated Federated Learning training framework

arXiv:2607. 19524v1 Announce Type: cross Abstract: Federated learning (FL) offers a promising approach to privacy-preserving clinical risk prediction, but its deployment remains limited by restricted data sharing, client heterogeneity, class imbalance, and the lack of realistic tabular electronic health record (EHR) benchmarks.

By Akarsh K Nair, Muhammad Arifur Rahman, Nicholas Shopland, Andy Burton, Jun He, Yuan Shen, David Baldwin, Emma O'Dowd, Amna Burzic, Mufti Mahmud, David J. Brown
arXiv Machine Learning
Aug 5

Federated generative event models for tokenized electronic health records

arXiv:2608. 02939v1 Announce Type: new Abstract: Electronic health record foundation models are limited by institutionally siloed data and substantial performance degradation under cross-site transfer.

By Michael C. Burkhart, Luke Solo, Inhyeok Lee, S'Khaja Charles, Zewei "Whiskey" Liao, Kaveri Chhikara, Dema Therese, Wan-Ting Liao, Catherine A. Gao, William F. Parker, Brett K. Beaulieu-Jones