arXiv:2606. 19950v1 Announce Type: cross Abstract: Multimodal Large Language Models (MLLMs) show great potential in medical tasks, but their elicited confidence often misaligns with actual accuracy, potentially leading to misdiagnosis or overlooking correct advice.
arXiv:2608.22323v1 Announce Type: new Abstract: The application of Large Language Models (LLMs) to diagnostic decision-making has garnered growing interest. However, existing benchmarks largely focus...
arXiv:2606. 28556v1 Announce Type: new Abstract: Recent advances in large language models and vision-language models have enabled reasoning over multimodal data, offering opportunities for clinical applications such as decision support and triaging.
PROVE is a black‑box hallucination detector for medical visual question answering that tailors its verification strategy to each question’s evidential structure. It classifies questions into three regimes, activates a subset of five operators per regime, and calibrates operator importance using deterministic question‑answer features to produce a risk score. On 8048 test samples across three medical VQA benchmarks and four state‑of‑the‑art vision‑language models, PROVE achieves an AUROC of 0.821, surpassing the best baseline by 0.159 with consistent improvements across all models and datasets.
arXiv:2607. 25933v1 Announce Type: cross Abstract: Clinical diagnostic evaluation should not only assess whether models can provide correct diagnoses, but also reflect the realities of clinical practice, including progressive disclosure of multimodal information, dynamic updating of diagnostic hypotheses, and continuous refinement of clinical reasoning.
arXiv:2609.06419v1 Announce Type: cross Abstract: Medical vision-language models (VLMs) require confidence that reflects both answer correctness and patient-specific visual evidence. Recent GRPO-base...
arXiv:2608. 08307v1 Announce Type: cross Abstract: Medical Visual Question Answering (VQA) requires aligning subtle visual evidence, including lesion texture, boundary sharpness, and diffuse density changes, with clinical language.
arXiv:2606. 27023v1 Announce Type: new Abstract: Multimodal large language models (MLLMs) applied to Medical Visual Question Answering (VQA) tend to produce overconfident outputs regardless of actual correctness, and existing verbalized confidence calibration methods, developed primarily for text only LLMs, do not account for the multimodal nature of medical image understanding.
MedProb is a lightweight probing framework that predicts multiple-choice medical visual question answering (Med‑VQA) answers directly from frozen vision‑language model (VLM) representations, avoiding free‑text generation. On datasets such as PATH‑VQA, SLAKE, and VQA‑RAD, MedProb extracts more answer‑relevant signal than prompting and outperforms both medical VLMs and agentic systems. The approach also narrows the performance gap between small and large models, shows that medical adaptation does not consistently improve linear decodability, and reveals positional biases in both prompting and generation.
The paper evaluates uncertainty estimation (UE) methods for clinical vision‑language models (VLMs) on visual question answering (VQA). Across 8 UE techniques and 12 VLMs, UE quality tracks model accuracy, degrading where performance is weakest, and fails to signal uncertainty when models are stressed by hiding the correct answer (NOTA perturbations). However, UE on unperturbed inputs reliably predicts which predictions will collapse under NOTA, suggesting UE can diagnose model fragility.
The paper introduces ThoughtMed-1M, a large-scale medical visual question answering dataset built from de‑identified images and clinician‑generated commentaries, designed to capture structured clinical reasoning and image‑text alignment. Using this dataset, the authors train FOLTMed, a foundational large language model that achieves state‑of‑the‑art performance on 42 medical VQA benchmarks, with a macro accuracy of 85.4% and improved factuality and similarity metrics over existing models.
arXiv:2604.02543v2 Announce Type: replace Abstract: As vision-language models (VLMs) are increasingly deployed in clinical decision support, more than accuracy is required: knowing when to trust thei...
The paper introduces MedREAL, a unified framework that aligns linguistic reasoning with spatial grounding for medical visual question answering and segmentation. MedREAL employs Seg Anchored Reasoning Pooling (SARP) to extract semantic evidence from segmentation tokens and a Reasoning-to-Visual (R2V) fusion mechanism to integrate these features into a segmentation pipeline. Using the newly created MedRAVS-13K dataset, MedREAL achieves superior performance, reporting 68.49% gIoU and 70.47% cIoU, and generates evidence masks that consistently match textual diagnoses.