The paper evaluates multimodal decision models, specifically CLEF and CLEF‑Flash, on 2,818 breast ultrasound images from three datasets (Dataset B, BUSI, BUS‑BRA). Using three different prompts—minimal labels, explicit classification, and sonographic criteria—the study reports accuracy, macro F1, balanced accuracy, precision, throughput, and latency. CLEF‑Flash with a clinical prompt achieves the highest accuracy across all datasets, while CLEF with a task‑guided prompt yields the best macro F1 and balanced accuracy on BUSI; however, all configurations underperform a majority‑class predictor on BUS‑BRA, highlighting frequent benign‑to‑malignant misclassifications.
By Tran Cao Minh, Hai Tran, Ha Minh Tan
Deep learning-based computer-aided diagnosis (CAD) systems have shown strong performance in breast cancer diagnosis, particularly for classification tasks in mammography. However, domain shifts across multi-site datasets remain a challenge, especially when models are applied to unseen domains.
arXiv:2511. 15968v2 Announce Type: replace-cross Abstract: External validation of breast ultrasound segmentation models remains limited because internal train--test splits do not capture domain shifts across imaging systems, acquisition protocols, and patient populations.
By Jingru Zhang, Saed Moradi, Ashirbani Saha
The study evaluates ten ImageNet‑pretrained deep learning models for classifying benign versus malignant breast cancer in the BreakHis histopathology dataset, using a patient‑level split. DenseNet121 achieved the highest performance with 99.4% accuracy and an AUC‑ROC of 0.999, outperforming all other models (p < 0.001). Explainability methods (Grad‑CAM, LIME, Integrated Gradients, LRP) consistently identified nuclei‑rich and glandular regions as key diagnostic features, demonstrating that transfer learning combined with explainable AI can produce accurate and interpretable breast cancer diagnostic tools.
By Sami Alnawali, Muhammad Atif Saeed, Abdul Hadi, Azka Atiq, Akhtar Jamil, Ahmad Din
The study evaluates lesion‑guided region‑of‑interest (ROI) deep learning for ovarian ultrasound classification, comparing it to global image, lesion contour, and contour‑based radiomics approaches across two public datasets. Using four deep‑learning architectures, the lesion‑guided ROI strategy achieved the highest accuracy (93.10% on MMOTU and 97.56% on OUD) with an AUC of 0.99, while requiring less annotation effort than contour‑based methods.
By Mehran Ahmad, Ali Abbasian Ardakani, Afshin Mohammadi, Alisa Mohebbi, Gernot Kronreif, Sepideh Hatamikia
arXiv:2607. 10188v1 Announce Type: cross Abstract: Breast cancer remains the most commonly diagnosed malignancy among women worldwide, yet accurate detection and characterization of breast masses in mammography remain challenging due to subtle intensity variations, heterogeneous tissue densities, and indistinct lesion boundaries that complicate radiological interpretation.
By Abu Fatema Mohammad Abdun Noor, Md Imam Ahasan, Md Samiul Ahasan, Kah Ong Michael Goh, S M Hasan Mahmud, Raihana Zannat
arXiv:2607. 26333v1 Announce Type: cross Abstract: Chest X-ray (CXR) machine learning relies heavily on automated evaluation using reference standards that aim to approximate clinical judgment.
By Panagiotis Fytas, Ian Selby, Clemens Karner, Judith Babar, Simon Baker, Jake Beckford, Timothy J. Sadler, Shahab Shahipasand, Arthikkaa Thavakumar, John Li Chen, Alex Sawer, Michael Roberts, Jonathan Weir-McCall, J. H. F. Rudd, Carola-Bibiane Sch\"onlieb, Anna Korhonen, Anna Breger
arXiv:2609.15225v1 Announce Type: new
Abstract: Objective: To develop an intelligent framework, termed CUA-Net, for the automated classification of congenital uterine anomalies (CUA) without requirin...
By Yueyue Xu, Yuhao Huang, Jiaxiao Deng, Yuanji Zhang, Haoming Zhang, Jiajia Qu, Shiying Zheng, Xiaomei Tang, Haining Chen, Chengcai Chen, Yiyi Wu, Xin Yang, Dong Ni
arXiv:2608. 10271v1 Announce Type: cross Abstract: Breast density classification is a critical component of breast cancer risk assessment, yet AI models often struggle to generalize across clinical sites due to vendor-specific acquisition styles.
By Hongyi Pan, Gorkem Durak, Halil Ertugrul Aktas, Andrea Mia Bejar, Mustafa Ege Seker, Nebile Alibeyoglu, Rumeysa Guclu, Rana Gunoz Comert Bozkurt, Sibel Ozkan Gurdal, Neslihan Cabioglu, Beyza Ozcinar, Ravza Yilmaz, Vahit Ozmen, Erkin Aribal, Sukru Mehmet Erturk, Yalda Zafari, Mohamed Mabrok, Kayhan Batmanghelich, Mohammad Yaqub, Ziyue Xu, Ulas Bagci
arXiv:2503.13309v3 Announce Type: replace-cross
Abstract: Despite advancements in Computer-Aided Diagnosis (CAD) systems, breast cancer remains one of the leading causes of cancer-related deaths amon...
By Farnoush Bayatmakou, Reza Taleei, Milad Amir Toutounchian, Arash Mohammadi
OncoVision is a privileged‑information training framework that learns from mammography images and clinical data during training but performs inference using only mammographic images. It employs an attention‑based encoder‑decoder to jointly segment masses, calcifications, axillary findings, and breast tissue, and predicts ten structured clinical features such as BI‑RADS. Two late‑fusion strategies (Independent and Dependent) integrate imaging, radiomic, and clinical information to improve diagnostic precision, and a retrospective multi‑reader study showed higher diagnostic confidence, reduced reading time, and segmentation accuracy comparable to or better than radiologists.
By Istiak Ahmed, Galib Ahmed, K. Shahriar Sanjid, Md. Tanzim Hossain, Md. Nishan Khan, Md. Misbah Khan, Md. Arifur Rahman, Sheikh Anisul Haque, Sharmin Akhtar Rupa, Mohammed Mejbahuddin Mia, Mahmud Hasan Mostofa Kamal, Md. Mostafa Kamal Sarker, M. Monir Uddin
ProtoCAM is an explainable few‑shot learning framework for classifying breast lesions in ultrasound images. It combines mask‑guided feature encoding, prototypical metric learning, and gradient‑based visual explanations to leverage limited annotated data. Evaluated on the BUSI dataset, ProtoCAM achieved a macro F1‑score of 0.910 in a 3‑way 5‑shot setting, outperforming standard supervised CNNs, with ResNet18 reaching 91.65% under 15‑shot conditions.
By Ashkan Ebadi