CAPS is a Clinically‑Verifiable Anatomy‑Prioritized Synthesis framework designed to impute missing MRI modalities for brain tumor segmentation. It uses a hybrid loss (L₁ + L_AFP + L_DualDice) to preserve deep anatomical features and topological boundaries, achieving high synthesis fidelity and robust segmentation (82.38% mean Dice) on the BraTS Adult Glioma dataset. The method also generalizes well to unseen cohorts and has been validated by blinded radiologists, who report improved image quality and clinical utility.
Multi-parametric MRI is the gold standard for neuro-oncology, yet acquiring complete 4-modality protocols may be unfeasible in real-world clinical practice. When handling missing modalities, existing...
arXiv:2606. 15457v1 Announce Type: cross Abstract: 3D FLAIR MRI is widely recommended as one of the standard MRI sequences for brain imaging in multiple sclerosis (MS), but publicly available MS datasets remain relatively small and vary across scanners, acquisition protocols, and lesion patterns.
SRUG is a supervised, fusion‑driven generator network designed for paired MRI sequence synthesis. It eliminates the generator‑discriminator competition by directly learning a deterministic source‑to‑target mapping, using a residual encoder, full‑resolution stem, and a nested multi‑scale decoder to preserve structural fidelity. Experiments on BraTS 2023 and IXI demonstrate competitive reconstruction quality and cross‑dataset transferability, supporting direct supervised generation as a practical approach for medical image translation.
arXiv:2606. 18354v1 Announce Type: cross Abstract: Recent advances in generative machine learning models have significantly improved medical imaging, offering promising solutions for data augmentation, privacy preservation, and improved model generalization.
arXiv:2602. 18400v3 Announce Type: replace-cross Abstract: Missing data problems, such as missing modalities in multi-modal brain MRI and missing slices in cardiac MRI, pose significant challenges in clinical practice.
arXiv:2607. 19137v1 Announce Type: cross Abstract: Inferring contrast enhancement from one pre-contrast breast MRI slice is underdetermined: post-contrast appearance contains physiological information that is not uniquely encoded in baseline anatomy.
Inferring contrast enhancement from one pre-contrast breast MRI slice is underdetermined: post-contrast appearance contains physiological information that is not uniquely encoded in baseline anatomy. Optimizing only paired pixel fidelity can suppress uncertain lesion enhancement, whereas adversarial or stochastic generative objectives can favor realistic post-contrast appearance without guaranteeing patient-specific lesion fidelity.
arXiv:2606. 24313v1 Announce Type: new Abstract: AI-driven image-to-image synthesis is rapidly advancing, with growing applications in medical imaging.
arXiv:2610.08983v1 Announce Type: new Abstract: Generative inpainting of brain MRI volumes is essential for synthesizing healthy tissue in pathological regions, improving the accuracy and reliability...
The paper introduces Missing Modality-Aware Local Temperature Scaling (MMA‑LTS), a post‑hoc voxel‑wise confidence calibration technique designed for multimodal brain tumor segmentation. MMA‑LTS adapts a temperature field based on which MRI modalities are present and a voxel‑wise difficulty score, addressing calibration errors that arise when specific modalities are missing. Experiments on BraTS 2020 and FeTS 2024 demonstrate that MMA‑LTS improves calibration while maintaining segmentation accuracy across various missing‑modality scenarios.
arXiv:2606. 19651v1 Announce Type: new Abstract: Three-dimensional (3D) brain MRI is central to clinical neurology and neuro-oncology, where generative models could augment under-represented cohorts, simulate disease trajectories, and support privacy-preserving data sharing.
arXiv:2512. 14937v2 Announce Type: replace-cross Abstract: Gliomas are the most common malignant brain tumors in adults and are among the most lethal.