FLAT: FLow-Aligned Training of Unrolled Networks for MRI Reconstruction proposes a new training method for unrolled neural networks used in MRI reconstruction. By interpreting unrolled networks as discretizations of conditional probability flows, the authors derive cascade parameters from Flow Matching and align intermediate reconstructions with the ideal Flow Matching trajectory. Experiments on three MRI datasets demonstrate that FLAT stabilizes the reconstruction trajectory across sub-networks and improves the final reconstruction quality.
By Kehan Qi, Saumya Gupta, Xiaoling Hu, Qingqiao Hu, Weimin Lyu, Yicun Wang, Chao Chen
arXiv:2607. 02998v1 Announce Type: cross Abstract: Controllable generative models of 3D medical images can synthesize volumes with specified clinical attributes, but this demands samples that are simultaneously high-fidelity, natively 3D, and faithful to the requested conditioning.
By Max Van Puyvelde, Halil Ibrahim Gulluk, Wim Van Criekinge, Olivier Gevaert
arXiv:2607. 02998v2 Announce Type: replace-cross Abstract: Controllable generative models of 3D medical images can synthesize volumes with specified clinical attributes, but this demands samples that are simultaneously high-fidelity, natively 3D, and faithful to the requested conditioning.
By Max Van Puyvelde, Halil Ibrahim Gulluk, Wim Van Criekinge, Olivier Gevaert
Whole-slide image (WSI) analysis remains computationally challenging due to the extremely large spatial resolution of slides and the sparse distribution of tumour regions. We propose an end-to-end reinforcement learning framework for sequential tumour segmentation directly on WSIs.
The paper introduces a high‑resolution Rectified Flow Matching model trained on 256×256 chest CT images to serve as a generative prior for CT reconstruction. A two‑stage training strategy—initial strong anatomically informed augmentation followed by fine‑tuning—helps mitigate overfitting and improve structural fidelity. When evaluated on various CT inverse problems, Flow Matching‑based reconstruction methods outperform diffusion‑based algorithms in PSNR, SSIM, and perceptual quality while requiring fewer sampling steps.
By Davide Evangelista
arXiv:2608. 08919v1 Announce Type: cross Abstract: During standard radiotherapy planning, repeated CT acquisitions are often required for patient registration, verification, and adaptive planning, resulting in increased cumulative X-ray dose.
By Alzahra Altalib, Chunhui Li, Christopher Hamill Taylor, Sankar Pillai, Alessandro Perelli
The paper introduces MAMA-FLUX.2, a conditional latent flow‑matching model built on FLUX.2-Klein-4B, designed to synthesize post‑contrast breast DCE‑MRI from pre‑contrast images for the MAMA‑SYNTH challenge. It encodes the pre‑contrast image as spatial conditioning and predicts the flow field for the post‑contrast latent, adapting the pretrained model with LoRA fine‑tuning and a regional training objective that combines global flow matching, tumor‑region supervision, and stable foreground regularization. Ablation studies show that moderate tumor and stable‑foreground weighting improves the balance between image fidelity and tumor‑region accuracy, with the best configuration achieving a strong trade‑off using LoRA rank 64/64, MHA_max 25, λ_tumor 0.25, and λ_stable 0.1.
By Kamil Kwarciak, Marek Wodzinski
arXiv:2608. 03430v1 Announce Type: cross Abstract: Four-dimensional cone beam CT (4D CBCT) is important for image-guided radiation therapy of thoracic cancers, but its use is limited by long scan times, causing high patient dose and motion/sparse-sampling artifacts.
By Ivo Herzig, Pascal Paysan, Daniel Barco, Marc Andr\'e Stadelmann, Frank-Peter Schilling, Igor Peterlik, Michal Walczak, Lijin Aryananda, Woo Sang Ahn, Rudolf Marcel F\"uchslin, Lukas Lichtensteiger
arXiv:2509. 21913v2 Announce Type: replace-cross Abstract: Background: Cone-beam computed tomography CBCT is a commonly used modality for image guided radiotherapy.
By Alzahra Altalib, Chunhui Li, Alessandro Perelli
arXiv:2606. 11025v1 Announce Type: new Abstract: Recent work has demonstrated that online reinforcement learning (RL) can substantially improve the quality and alignment of flow matching models for image and video generation.
By Bowen Ping, Xiangxin Zhou, Penghui Qi, Minnan Luo, Liefeng Bo, Tianyu Pang
Generating CT volumes from MRI and CBCT can improve treatment planning in adaptive radiotherapy while avoiding additional radiation exposure. However, direct regression of CT intensities is challenged by the inherently high dynamic range and long-tailed distributions, thereby averaging out sparse yet clinically important structures.
arXiv:2606. 30951v1 Announce Type: cross Abstract: Micro-ultrasound ($\mu$US) is a new, emerging, and promising imaging modality for prostate cancer (PCa) detection, but accurate identification of suspicious tissue remains highly dependent on clinical experience, leading to substantial inter-observer variability.
By Mohammad Mahdi Abootorabi, Sina Namazi, Armin Saadat, Lyuyang Wang, Obed Dzikunu, Paul F. R. Wilson, Zhuoxin Guo, Brian Wodlinger, Parvin Mousavi, Purang Abolmaesumi