arXiv:2606. 26764v1 Announce Type: cross Abstract: Developing robust artificial intelligence models for 4D (3D + time) medical imaging is constrained by limited annotated data, inter-device domain shifts, and privacy restrictions.
By Yiheng Cao, Gustavo Andrade-Miranda, Jiatian Zhang, Lingxiao Zhao, Xin Gao
FlowMoDL is an unrolled neural network designed for highly accelerated 4D flow MRI reconstruction, optimizing both anatomical magnitude and phase-derived velocity accuracy. It alternates a learned (3+1)D spatiotemporal denoiser with conjugate‑gradient data‑consistency updates, using a dual‑pathway conditioning scheme to handle acceleration factors from 10× to 50×. Trained with a deep‑supervision composite loss that penalizes velocity magnitude and angular errors, FlowMoDL outperforms classical and deep‑learning baselines on the multi‑center CMRx4DFlow dataset, achieving superior gradient‑step efficiency and robust convergence across all acceleration factors.
By Tristan Gottwald, Michelle Bruch, Mubashir-Ul Hassan, Fatma Alickovic, Milan Kloiber, Daniel Tenbrinck, Torsten Panholzer, Melanie Schaller, Jana Hutter
The paper introduces a high‑resolution Rectified Flow Matching model trained on 256×256 chest CT images to serve as a generative prior for CT reconstruction. A two‑stage training strategy—initial strong anatomically informed augmentation followed by fine‑tuning—helps mitigate overfitting and improve structural fidelity. When evaluated on various CT inverse problems, Flow Matching‑based reconstruction methods outperform diffusion‑based algorithms in PSNR, SSIM, and perceptual quality while requiring fewer sampling steps.
By Davide Evangelista
Developing robust artificial intelligence models for 4D (3D + time) medical imaging is constrained by limited annotated data, inter-device domain shifts, and privacy restrictions. To address this, we propose a 4D controllable generative framework for anatomically consistent data augmentation.
The paper explores large‑scale pretraining to enhance deep learning‑based geometric distortion correction for diffusion‑weighted imaging (DWI). By framing the task as image reconstruction, the authors compare a non‑pretrained baseline with self‑supervised and generative pretrained models, finding that the cWDM model yields the best quantitative and qualitative results. When applied to low‑resource, high‑throughput settings in a low‑ and middle‑income country, the pretrained models faced transferability issues, but aligning images to a common standard space improved predictions, indicating that harmonized preprocessing can aid cross‑domain deployment.
By Saroj Khanal, Yashawant Kumar Yadav, Kritam Bhattarai, Jeevan Neupane, Shristi Subedi, Saship Gwachha, Manish Kumar Tiwari, Dong Zhang, Confidence Raymond, Aondona Moses Iorumbur, Udunna Anazodo, Surendra Maharjan, Bishesh Khanal, Mahesh Shakya, Pralhad Kumar Shrestha
The paper introduces Conditional Diffusion Posterior Alignment (CDPA), a method that scales diffusion-based sparse‑view CT reconstruction to large 3D volumes by conditioning a 2D U‑Net diffusion model on an initial 3D reconstruction and enforcing data‑consistency alignment. CDPA addresses high memory demands, limited 3D training data, and slice‑wise inconsistencies, achieving state‑of‑the‑art performance on synthetic and real Cone Beam CT data. The authors also demonstrate that the same approach improves fast denoising U‑Nets, delivering near‑diffusion quality at a fraction of the computational cost.
By Luis Barba, Johannes Kirschner, Benjamin Bejar
FLAT: FLow-Aligned Training of Unrolled Networks for MRI Reconstruction proposes a new training method for unrolled neural networks used in MRI reconstruction. By interpreting unrolled networks as discretizations of conditional probability flows, the authors derive cascade parameters from Flow Matching and align intermediate reconstructions with the ideal Flow Matching trajectory. Experiments on three MRI datasets demonstrate that FLAT stabilizes the reconstruction trajectory across sub-networks and improves the final reconstruction quality.
By Kehan Qi, Saumya Gupta, Xiaoling Hu, Qingqiao Hu, Weimin Lyu, Yicun Wang, Chao Chen
The paper introduces CM-RED, a fast MRI reconstruction method that combines a pretrained consistency model with the regularization by denoising framework. By integrating controlled noise injection into accelerated proximal gradient updates, CM-RED achieves high‑quality reconstructions on fastMRI knee and brain datasets with only four network function evaluations. It consistently outperforms existing diffusion‑ and consistency‑based approaches in quantitative metrics, visual fidelity, and robustness to hyperparameter changes.
By Merve G\"ulle, Junno Yun, Ya\c{s}ar Utku Al\c{c}alar, Mehmet Ak\c{c}akaya
arXiv:2603. 05693v2 Announce Type: replace-cross Abstract: Accurate longitudinal analysis of brain MRI is often hindered by evolving lesions, which bias automated neuroimaging pipelines.
By Zahra Karimaghaloo, Dumitru Fetco, Haz-Edine Assemlal, Hassan Rivaz, Douglas L. Arnold
arXiv:2603. 00205v2 Announce Type: replace-cross Abstract: Generative models, particularly Diffusion Models (DM), have shown strong potential for Computed Tomography (CT) reconstruction serving as expressive priors for solving ill-posed inverse problems.
By Jiayang Shi, Lincen Yang, Zhong Li, Tristan van Leeuwen, Daniel M. Pelt, K. Joost Batenburg
arXiv:2605.20470v2 Announce Type: replace-cross
Abstract: Cone-beam CT (CBCT) is routinely acquired during radiotherapy for patient setup, but its quantitative reliability is degraded by scatter, noi...
By Alzahra Altalib, Chunhui Li, Haytham Ahmad Alewaidat, Khaled Z. Alawneh, Ahmad Awad Qandeel, Alessandro Perelli
arXiv:2606. 24313v1 Announce Type: new Abstract: AI-driven image-to-image synthesis is rapidly advancing, with growing applications in medical imaging.
By Martin Valls (UFR SFA), Pascal Bourdon (UFR SFA), Christine Fernandez-Maloigne (LabCom I3M), Guillaume Herpe (CHU Poitiers -- Radio, DACTIM-MIS), David Helbert (UFR SFA)