arXiv AI

H2: A Dual Hybrid Semantic Data Lake Architecture for Medical Data Harmonization with Human-In-the-Loop verified, LLM Driven Metadata Annotation System

arXiv:2608. 08056v1 Announce Type: new Abstract: Medical data, by its nature, exhibit a high degree of heterogeneity on multiple levels ranging from (a) different modalities like images, text and time series, (b) diverse tabular schemata introduced by institutions and (c) completely unstructured textual information data provided by healthcare professionals.

arXiv AI
Sep 3

Unifying biomedical knowledge in a modern multimodal graph

OptimusKG is a multimodal biomedical labeled property graph that integrates structured and semi‑structured resources to preserve detailed, type‑specific metadata across molecular, anatomical, clinical, and environmental domains. The graph contains nearly 191,000 nodes, over 21.8 million edges, and more than 67 million property instances derived from 18 ontologies, with a top‑level schema that enforces node and edge constraints while retaining granular provenance. Validation using the PaperQA3 agent found that 70.0% of sampled edges are supported by literature evidence, and the graph offers a standardized resource for machine learning, knowledge‑grounded retrieval, and hypothesis generation in biomedical research.

By Lucas Vittor, Ayush Noori, I\~naki Arango, Joaqu\'in Polonuer, Sam Rodriques, Andrew White, David A. Clifton, Marinka Zitnik
arXiv AI
Jul 28

Retrieval-Augmented Generation of Ontologies from Relational Databases

arXiv:2506. 01232v2 Announce Type: replace-cross Abstract: Deriving OWL ontologies from relational database schemas supports semantic interoperability and downstream tasks such as knowledge graph population, ontology-based data access, graph-based learning, and automated reasoning.

By Nadeen Fathallah, Mojtaba Nayyeri, Athish A Yogi, Ratan Bahadur Thapa, Hans-Michael Tautenhahn, Anton Schnurpel, Steffen Staab
arXiv AI
Sep 15

EvoOntology: A Self-Evolving Ontology Layer for Data Agents

EvoOntology introduces a self‑evolving ontology layer for data agents, encapsulating the ontology as an MCP server with schema, content, and tool layers. It enables agents to query and interact with the ontology at runtime, using a builder agent for autonomous construction and a self‑evolution loop that refines the ontology through attribution‑guided edits validated by backbone‑conditional evaluation. Experiments on three data‑agent benchmarks with four LLM backbones show that EvoOntology consistently outperforms strong baselines and existing semantic‑layer approaches, effectively bridging the agent‑data gap for heterogeneous data.

By Meiduo Chong, Shaolei Zhang, Ju Fan, Xiaoyong Du
arXiv AI
Jul 7

Medi-Gemma: A Hybrid Clinical Decision Support System Integrating Deterministic EMR Analytics and Retrieval-Augmented Generation

arXiv:2607. 04907v1 Announce Type: new Abstract: Deploying Large Language Models (LLMs) in high-stakes clinical settings remains limited by structural hallucinations, weak deterministic reasoning over tabular patient data, and omissions in vector retrieval.

By Mohammed Saim Ahmed Quadri, Yunzhe Xue, Justin W. Ady, Usman Roshan