arXiv:2606. 07633v1 Announce Type: cross Abstract: Accurate classification of nuclei subtypes in histopathology images is critical for downstream tasks including tumor grading, immune infiltrate quantification, and prognosis prediction.
The paper introduces an unsupervised domain adaptation framework that aligns redundancy-reducing features to enable accurate 3D segmentation of cone-beam CT (CBCT) without target-domain annotations or inference-time adaptation. The method is architecture-agnostic, working with both CNN-based and ViT-based foundation models, and is evaluated on two liver segmentation benchmarks for interventional vascular procedures and radiation therapy. Results show that even large pretrained segmentation networks need explicit feature-space bridging to generalize across diagnostic CT and CBCT, and the proposed approach consistently outperforms existing pretrained foundation models and UDA strategies.
nnFoundation introduces complementary convolutional and transformer-based 3D foundation models for radiology, trained on 2.1 million CT, MRI, and PET volumes from 125 datasets. The models are evaluated on 108 tasks—including segmentation, detection, classification, report generation, and image retrieval—under domain shift, low-data, and low-compute scenarios, consistently outperforming prior 3D foundation models and training from scratch. Performance varies by task type, with convolutional models excelling at spatially localized tasks and transformer models at global semantic reasoning, and dynamic alignment with dataset characteristics further enhances transferability.
arXiv:2606. 13007v1 Announce Type: cross Abstract: Clustering is fundamental to scRNA-seq analysis, serving as a cornerstone for identifying cell populations and resolving tissue heterogeneity.
arXiv:2610.31902v1 Announce Type: new Abstract: Objectives: In the area of digital pathology, nucleus segmentation is an essential step for quantitative analysis; however, high nuclear density and st...
The paper proposes a scalable framework that uses cell-level spatial transcriptomics (ST) as weak supervision for nuclei classification in histopathology images. By converting gene expression profiles into cell-type labels and leveraging nucleus masks from ST data, the method automatically generates image-label pairs without manual annotation. Evaluations on unseen tissues show that this approach achieves segmentation and classification performance comparable to conventional supervised methods while requiring fewer manually annotated datasets.
The paper presents a 3D foundation model for light sheet fluorescence microscopy (LSM) that is pretrained on a large curated set of 3D images from various organisms, stains, and imaging protocols. By jointly optimizing for masked reconstruction and image‑text alignment, the model learns transferable volumetric representations that dramatically reduce the need for annotated data. The pretrained backbone enables efficient few‑shot adaptation to downstream tasks such as segmentation, classification, and deblurring, consistently outperforming baselines according to standard metrics and expert evaluation.
arXiv:2605.16392v2 Announce Type: replace-cross Abstract: Multiple instance learning (MIL) is the dominant framework for whole-slide image analysis in computational pathology, typically combining a f...
arXiv:2606. 17702v1 Announce Type: cross Abstract: Characterising the tumour microenvironment (TME) from routine H&E-stained histology images requires simultaneous cell segmentation, feature extraction, and interpretable clinical reporting.
arXiv:2510.14383v4 Announce Type: replace Abstract: Accurate brain tumor segmentation is significant for clinical diagnosis and treatment but remains challenging due to tumor heterogeneity. Mamba-bas...
arXiv:2608.23745v1 Announce Type: cross Abstract: Accurate brain tumor segmentation from magnetic resonance imaging (MRI) is essential for diagnosis, treatment planning, surgical guidance, and diseas...
arXiv:2512. 14937v2 Announce Type: replace-cross Abstract: Gliomas are the most common malignant brain tumors in adults and are among the most lethal.