arXiv AI

Bringing analytic rigor to agentic AI for science: The Brain Researcher platform for neuroimaging data analysis

arXiv:2608. 19902v1 Announce Type: new Abstract: AI agents can execute scientific analyses, but an analytic output becomes a defensible claim only after alternatives are weighed and the claim is limited to what the evidence supports.

arXiv Machine Learning
Jul 1

The Calibration Turn in AI-Assisted Research: A Conceptual and Methodological Framework for Evidence-Licensed Claims

arXiv:2606. 31273v1 Announce Type: new Abstract: AI-assisted research has entered a stage in which the central question is not only whether systems can generate hypotheses, run experiments, or produce manuscripts, but whether their scientific claims are calibrated to the evidence that supports them.

By Hongmin Li
arXiv AI
Jun 11

AI Coding Agents in Social Science: Methodologically Diverse, Empirically Consistent, Interpretively Vulnerable

arXiv:2606. 11456v1 Announce Type: cross Abstract: The deployment of LLM-based agents in scientific analysis raises opposing concerns: that agents may reduce methodological diversity, or that they may amplify the analytic flexibility through which researchers reach motivated conclusions.

By Meysam Alizadeh, Fabrizio Gilardi, Mohsen Mosleh, Enkelejda Kasneci
arXiv AI
Jun 8

Act As a Real Researcher: A Suite of Benchmarks Evaluating Frontier LLMs and Agentic Harnesses in Research Lifecycle

arXiv:2606. 07462v1 Announce Type: new Abstract: As foundation models advance and agent scaffolding becomes increasingly sophisticated, agents have demonstrated remarkable proficiency in complex, long-horizon coding tasks and even autonomous experiment execution.

By Jiayu Wang, Weijiang Lv, Bowen Fu, Jing Fu, Jiayi Song, Lingyu Zhang, Lanxuan Xue, Luodi Chen, Zepeng Xin, Kaiyu Li, Xiangyong Cao
arXiv AI
Jun 9

A case study of evaluating AI agents on a neuroscience data-to-discovery pipeline

arXiv:2606. 07718v1 Announce Type: new Abstract: Agentic AI tools offer a promising path to automating software development bottlenecks in scientific research pipelines, particularly for stages that take domain experts days to months to build, where scientists care about correctness and robustness, not implementation details.

By Kai A. Horstmann, Ethan Lin, Alice A. Robie, Jennifer J. Sun, Kristin Branson
arXiv AI
Sep 18

ScientistTwo: Pioneering the Human Knowledge Frontier with Autonomous AI

The paper introduces ScientistTwo, a fully autonomous multi‑agent framework that takes a scientific problem, establishes baselines, generates hypotheses, and coordinates specialized agents to conduct an end‑to‑end discovery cycle without human intervention. It rigorously tests and refines its methods through automated experiments, ablation studies, and a closed‑loop peer‑review engine. Benchmarking against top conferences (ICLR, ICML, NeurIPS) shows that ScientistTwo produces expert‑level, publishable papers and codebases that outperform human state‑of‑the‑art models and receive higher review ratings under automated AI review.

By Jaehyun Nam, Jinsung Yoon, Yanzhou Pan, Yubo Wang, Rui Meng, Parthasarathy Ranganathan, Tomas Pfister
arXiv AI
Sep 7

TruthInsightBench: An Evidence-Grounded Benchmark for Automated Evaluation of Open-Ended Scientific Discovery Agents

TruthInsightBench is a new benchmark designed to evaluate automated scientific discovery agents by presenting them with 40 blind tasks drawn from peer‑reviewed studies across ten domains. Each task provides only a neutral objective and frozen data, withholding source conclusions, expected values, and analysis paths, forcing agents to determine which claim the data support. A fixed LLM‑based judge scores agents on evidentiary maturity across six dimensions, using 29 artifact‑grounded items, enabling fully automated, repeatable evaluation without human grading.

By Zhibo Yang, Chen Zhang, Yuewei Zhang, Hao Wang
arXiv AI
Jun 11

Can AI Agents Synthesize Scientific Conclusions?

arXiv:2606. 11337v1 Announce Type: new Abstract: Scientific AI agents increasingly retrieve evidence, reason across sources, and synthesize conclusions used in consequential decisions.

By Hayoung Jung, Pedro Viana Diniz, Jos\'e Reinaldo Corr\^ea Roveda, Abner Fernandes da Silva, Haeun Jung, Enoch Tsai, Aleksandra Korolova, Manoel Horta Ribeiro