Towards End-to-End Automation of AI Research
arXiv:2606. 15497v1 Announce Type: new Abstract: The automation of science is a long-standing ambition in the field of AI.
arXiv:2608. 13558v1 Announce Type: new Abstract: Recent advances in foundation models have enabled AI scientists to automate increasingly complete research workflows, from hypothesis generation and code execution to manuscript preparation.
arXiv:2606. 15497v1 Announce Type: new Abstract: The automation of science is a long-standing ambition in the field of AI.
arXiv:2608. 05179v1 Announce Type: cross Abstract: Large language model (LLM) agents are increasingly used across the scientific research lifecycle: ideation, literature search, experiment design and execution, analysis, manuscript drafting, and review.
OpenDiscoveryTrace is a public dataset of 558 complete AI scientific agent trajectories that records the reasoning process—thoughts, tool calls, observations, errors, revision triggers, and confidence—across 124 scientific tasks in drug discovery, materials science, genomics, and literature analysis. The dataset includes seven models (three frontier models and four open‑weight models) and 60 live‑retrieval variants, providing a balanced view of performance and error patterns. Pilot analysis shows that process traces reveal behavioral differences invisible to output‑only evaluation, such as differing error rates and types among frontier models.
arXiv:2607. 15079v1 Announce Type: new Abstract: Understanding the brain increasingly depends on integrating evidence across scales, modalities, and disciplines.
The paper introduces ScientistTwo, a fully autonomous multi‑agent framework that takes a scientific problem, establishes baselines, generates hypotheses, and coordinates specialized agents to conduct an end‑to‑end discovery cycle without human intervention. It rigorously tests and refines its methods through automated experiments, ablation studies, and a closed‑loop peer‑review engine. Benchmarking against top conferences (ICLR, ICML, NeurIPS) shows that ScientistTwo produces expert‑level, publishable papers and codebases that outperform human state‑of‑the‑art models and receive higher review ratings under automated AI review.
arXiv:2606. 11337v1 Announce Type: new Abstract: Scientific AI agents increasingly retrieve evidence, reason across sources, and synthesize conclusions used in consequential decisions.
arXiv:2603. 01421v3 Announce Type: replace Abstract: While large language models accelerate scientific discovery, existing agents face severe limitations in adaptability, domain generalization, and multimodal scalability, often struggling to autonomously process raw, domain-specific experimental data.
arXiv:2609.07611v1 Announce Type: new Abstract: Scientific ideation is the capacity to formulate novel and testable hypotheses from scientific evidence, and autonomous AI scientists depend on it. Exi...
arXiv:2606. 12736v1 Announce Type: new Abstract: AI agents are increasingly being developed to accelerate scientific discovery, yet their practical capabilities in real research settings remain poorly understood.
arXiv:2409. 11363v2 Announce Type: replace-cross Abstract: AI agents have the potential to aid users on a variety of consequential tasks, including conducting scientific research.
arXiv:2606. 31229v1 Announce Type: new Abstract: Ideation plays a pivotal role in scientific discovery.
arXiv:2606. 00644v1 Announce Type: new Abstract: AI research often requires decisions before future evidence exists: which bottleneck to attack, which direction to pursue, or where a project should be positioned.