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An Interpretable Deep Learning Framework for Discovery and Clinical Validation of Deep Radiomic Signatures in Tumor Classification

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Imaging signatures are quantitative features extracted from medical images that provide clinically meaningful information for tumor diagnosis, characterization, prognosis, and treatment planning. Although deep learning has shown great potential for imaging signature discovery, its limited interpretability remains a major barrier to clinical adoption.

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arXiv AI
Jul 7

An Interpretable Deep Learning Framework for Discovery and Clinical Validation of Deep Radiomic Signatures in Tumor Classification

arXiv:2607. 03593v1 Announce Type: cross Abstract: Imaging signatures are quantitative features extracted from medical images that provide clinically meaningful information for tumor diagnosis, characterization, prognosis, and treatment planning.

By Chengkun Sun, Jinqian Pan, Renjie Liang, Zhengkang Fan, Xin Miao, Yi Guo, Mei Liu, Muxuan Liang, Russell Terry, Jie Xu
arXiv AI
Sep 15

ProtoCAM: Interpretable Few-Shot Mask-Guided Prototypical Learning for Breast Lesion Classification in Ultrasound Imaging

ProtoCAM is an explainable few‑shot learning framework for classifying breast lesions in ultrasound images. It combines mask‑guided feature encoding, prototypical metric learning, and gradient‑based visual explanations to leverage limited annotated data. Evaluated on the BUSI dataset, ProtoCAM achieved a macro F1‑score of 0.910 in a 3‑way 5‑shot setting, outperforming standard supervised CNNs, with ResNet18 reaching 91.65% under 15‑shot conditions.

By Ashkan Ebadi