arXiv Machine Learning

Data-Efficient and Interpretable Classification of Circulating Tumor Cell Phenotypes in Microfluidic Devices via Deep Learning

arXiv:2608. 16870v1 Announce Type: new Abstract: Accurate classification of circulating tumor cell (CTC) phenotypes can provide valuable information for assessing metastatic potential.

arXiv Machine Learning
Aug 5

A Physics-Flavored Transformer Network for Parametrizing Contraction Dynamics of Engineered Skeletal Muscle Tissues

arXiv:2608. 03927v1 Announce Type: new Abstract: Engineered Skeletal Muscle Tissues (ESMs) have become a key structure for biomedical disease modeling and pharmacological screening, yet their functional characterization often relies on simplistic metrics like peak force, discarding critical kinetic information.

By Mattias Luber, Timo Betz
arXiv AI
Sep 25

A Multimodal 3D Foundation Model for Light Sheet Fluorescence Microscopy Enables Few-Shot Segmentation, Classification, and Deblurring

The paper presents a 3D foundation model for light sheet fluorescence microscopy (LSM) that is pretrained on a large curated set of 3D images from various organisms, stains, and imaging protocols. By jointly optimizing for masked reconstruction and image‑text alignment, the model learns transferable volumetric representations that dramatically reduce the need for annotated data. The pretrained backbone enables efficient few‑shot adaptation to downstream tasks such as segmentation, classification, and deblurring, consistently outperforming baselines according to standard metrics and expert evaluation.

By Adina Scheinfeld, Haotan Zhang, Shang Mu, Rudolf L. M. van Herten, Lucas Stoffl, Ali Erturk, Zhuhao Wu, Johannes C. Paetzold
arXiv AI
Jul 2

A Multi-Resolution Finite-Volume Inspired Deep Learning Framework for Spatiotemporal Dynamics Prediction

arXiv:2607. 00460v1 Announce Type: cross Abstract: Predicting complex spatiotemporal dynamics in physical processes often demands computationally expensive numerical methods or data-driven neural networks that suffer from high training costs, error accumulation, and limited generalizability to unseen parameters.

By Xin-Yang Liu, Xiantao Fan, Jian-Xun Wang
arXiv Machine Learning
Aug 17

Learning Unsteady Aneurysm Hemodynamics with Physics-Informed DeepONets

arXiv:2608. 13629v1 Announce Type: cross Abstract: Clinically actionable, patient-specific hemodynamic assessment, specifically wall shear stress, vortex structure and pressure distributions, is critical for determining risky or unfavorable evolution in Abdominal Aortic Aneurysms (AAA).

By Oscar L. Cruz-Gonzalez, Val\'erie Deplano, Badih Ghattas
arXiv AI
Jul 7

An Interpretable Deep Learning Framework for Discovery and Clinical Validation of Deep Radiomic Signatures in Tumor Classification

arXiv:2607. 03593v1 Announce Type: cross Abstract: Imaging signatures are quantitative features extracted from medical images that provide clinically meaningful information for tumor diagnosis, characterization, prognosis, and treatment planning.

By Chengkun Sun, Jinqian Pan, Renjie Liang, Zhengkang Fan, Xin Miao, Yi Guo, Mei Liu, Muxuan Liang, Russell Terry, Jie Xu
arXiv Machine Learning
Aug 27

FlowMoDL: Model-Based Deep Learning with Conjugate-Gradient Data Consistency for Highly Accelerated 4D Flow MRI Reconstruction

FlowMoDL is an unrolled neural network designed for highly accelerated 4D flow MRI reconstruction, optimizing both anatomical magnitude and phase-derived velocity accuracy. It alternates a learned (3+1)D spatiotemporal denoiser with conjugate‑gradient data‑consistency updates, using a dual‑pathway conditioning scheme to handle acceleration factors from 10× to 50×. Trained with a deep‑supervision composite loss that penalizes velocity magnitude and angular errors, FlowMoDL outperforms classical and deep‑learning baselines on the multi‑center CMRx4DFlow dataset, achieving superior gradient‑step efficiency and robust convergence across all acceleration factors.

By Tristan Gottwald, Michelle Bruch, Mubashir-Ul Hassan, Fatma Alickovic, Milan Kloiber, Daniel Tenbrinck, Torsten Panholzer, Melanie Schaller, Jana Hutter
arXiv AI
Jul 21

GigaPath-Flash and GigaTIME-Flash: Efficient Pathology Foundation Models for Whole-Slide and Tumor Microenvironment Analysis

arXiv:2607. 18218v1 Announce Type: cross Abstract: Foundation models have emerged as a driving force in computational pathology, with the potential to transform cancer diagnosis, prognosis, and treatment selection by learning transferable representations from large-scale histopathology data.

By Naoto Usuyama, Jeya Maria Jose Valanarasu, Sicong Yao, Hanwen Xu, Jaspreet Bagga, Guanghui Qin, Robert E. Kramer, Cliff Wong, Soohee Lee, Hao Qiu, Theodore Zhengde Zhao, Racheli Ben Shimol, Angela Crabtree, Kevin Matlock, Eduardo Alejandro Lozano Garcia, Naiteek Sangani, Alberto Santamaria-Pang, Jason Entenmann, Alexandra Q. Bartlett, Bill J. Wright, Bernard A. Fox, Brian Piening, Sheng Zhang, Sheng Wang, Tristan Naumann, Carlo Bifulco, Hoifung Poon