arXiv Machine Learning

TVT-PAPD: Pathology-Aware Prototype Distillation for Self-Supervised Whole Slide Image Classification

arXiv:2607. 10406v1 Announce Type: cross Abstract: Self-supervised learning (SSL) has emerged as an effective paradigm for learning transferable representations from large-scale unlabeled whole slide images (WSIs).

arXiv AI
Jun 8

DaX: Learning General Pathology Representations Across Scales

arXiv:2606. 06983v1 Announce Type: cross Abstract: Computational pathology requires visual representations that transfer across diverse clinical endpoints and remain robust to variation in magnification, staining, scanner type, slide preparation, and input resolution.

By Bokai Zhao, Yiyang Zhang, Long Bai, Tai Ma, Hanqing Chao, Minfeng Xu
arXiv AI
Sep 1

Towards Accurate and Lightweight Peripheral Neuroblastic Tumor Diagnosis via Contrastive Multi-scale Pathological Image Analysis

The paper introduces CoPath, a lightweight framework for diagnosing peripheral neuroblastic tumors (pNTs) from whole-slide images. CoPath combines CoHisNet, a multi‑scale feature‑fusion network that replaces traditional MLPs with Kolmogorov‑Arnold Network layers for efficient nonlinear modeling, and PathVote, which aggregates patch‑level predictions using pathology‑informed priors. Experiments on a private pNT cohort and the public BreakHis dataset show that CoPath matches or surpasses existing classifiers while reducing computational complexity.

By Zhu Zhu, Shuo Jiang, Jingyuan Zheng, Yawen Li, Yifei Chen, Manli Zhao, Weizhong Gu, Feiwei Qin, Jinhu Wang, Gang Yu
arXiv AI
Jun 12

BrainDINO: A Brain MRI Foundation Model for Generalizable Clinical Representation Learning

arXiv:2604. 27277v3 Announce Type: replace-cross Abstract: Brain MRI underpins a wide range of neuroscientific and clinical applications, yet most learning-based methods remain task-specific and require substantial labeled data.

By Yizhou Wu, Shansong Wang, Yuheng Li, Mojtaba Safari, Mingzhe Hu, Chih-Wei Chang, Harini Veeraraghavan, Xiaofeng Yang
arXiv Computer Vision
Sep 11

PathoHR: Breast Cancer Survival Prediction on High-Resolution Pathological Images

PathoHR is a new pipeline for predicting breast cancer survival from high‑resolution pathological images. It uses a plug‑and‑play Vision Transformer to enhance patch‑wise whole slide image representations, evaluates multiple similarity metrics to optimize feature learning, and shows that smaller, enhanced patches can match or surpass the accuracy of larger raw patches while cutting computational cost. The authors provide experimental evidence that this approach improves both accuracy and efficiency in computational pathology.

By Yang Luo, Shiru Wang, Jun Liu, Jiaxuan Xiao, Rundong Xue, Zeyu Zhang, Hao Zhang, Yu Lu, Yang Zhao, Yutong Xie
arXiv AI
Sep 3

ORB-SVM : An Innovative Hybrid Framework for Efficient Brain Tumor Detection from MRI Scans

The paper presents ORB-SVM, a hybrid framework that combines the ORB algorithm for feature extraction with a Support Vector Machine for classifying brain tumors in MRI scans. It achieves a 99.5% reduction in data size while preserving key diagnostic features, and reports a 97.5% classification accuracy on the Br35H dataset. This approach offers a resource‑efficient alternative to deep learning models, reducing computational cost and data requirements.

By Amirhosein Azarpour
arXiv Computer Vision
4d ago

HERO: Histology Encoder for Robust Representation in Oncology

HERO (Histology Encoder for Robust Representation in Oncology) is a ViT‑G/14 pathology foundation model trained with DINO and iBOT objectives and refined using high‑resolution Gram anchoring on a 500‑million‑tile corpus from about 575,000 clinical whole‑slide images. It demonstrates superior robustness to center, scanner, and stain variation compared to other state‑of‑the‑art foundation models, while maintaining competitive performance on tile‑level classification, segmentation, and gene‑expression prediction. Across 39 slide‑level clinical tasks, HERO ranks first on average and achieves the best average rank across six benchmark frameworks under an equal‑weighted analysis.

By Zhi Li (Caris Life Sciences, Irving, TX, United States), Eghbal Amidi (Caris Life Sciences, Irving, TX, United States), Yating Cheng (Caris Life Sciences, Irving, TX, United States), Tyson Dawson (Caris Life Sciences, Irving, TX, United States), Gorkem Can Ates (Caris Life Sciences, Irving, TX, United States), Shuzhen Kuang (Caris Life Sciences, Irving, TX, United States), Norsang Lama (Caris Life Sciences, Irving, TX, United States), Md Ashequr Rahman (Caris Life Sciences, Irving, TX, United States), Zhiying Lu (Caris Life Sciences, Irving, TX, United States), Elisabeth K. Kong (Caris Life Sciences, Irving, TX, United States), Milan Radovich (Caris Life Sciences, Irving, TX, United States), David Spetzler (Caris Life Sciences, Irving, TX, United States), Matthew Oberley (Caris Life Sciences, Irving, TX, United States), George W. Sledge (Caris Life Sciences, Irving, TX, United States), Ming Chen (Caris Life Sciences, Irving, TX, United States)
arXiv Computer Vision
6d ago

LadderMIL: Multiple Instance Learning with Coarse-to-Fine Self-Distillation

arXiv:2502.02707v5 Announce Type: replace Abstract: Multiple Instance Learning (MIL) for whole slide image (WSI) analysis in computational pathology often neglects instance-level learning as supervis...

By Shuyang Wu, Yifu Qiu, Ines P. Nearchou, Sandrine Prost, Jonathan A. Fallowfield, Hideki Ueno, Hitoshi Tsuda, David J. Harrison, Hakan Bilen, Timothy J. Kendall