arXiv AI
Whole-Slide Image Analysis under Realistic Few-Shot Annotation Protocols
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arXiv Computer Vision
Sep 28
Exploiting Spatial Structure for Transductive Few-Shot Classification of Whole-Slide Images
The paper introduces SlideTIM, a transductive few‑shot classification method tailored for whole‑slide images (WSIs). SlideTIM extends the LC‑TIM approach by adding a spatial‑latent regularizer and a class‑distribution prior, ensuring that spatially and semantically similar patches receive consistent predictions and that predicted class proportions are calibrated. Experiments on four histology datasets show that SlideTIM outperforms existing TIM variants, boosting macro‑F1 scores by up to 8.1 percentage points over the best baseline and 19.4 percentage points over zero‑shot predictions at one shot.
arXiv Computer Vision
Aug 25
LanGuSTE: Language-Guided Coarse-to-Fine Patch Selection for Efficient Whole Slide Image Analysis
LanGuSTE is a patch‑selection framework for whole slide image analysis that uses vision‑language models and large language model knowledge. It introduces Cross‑Scale Visual Prompt Tuning to align low‑resolution and high‑resolution patches, and a coarse‑to‑fine selection module that encodes only informative high‑resolution patches. Experiments show LanGuSTE cuts overall processing time to about one‑third of the baseline while matching or surpassing diagnostic performance of exhaustive and state‑of‑the‑art methods.
arXiv Computer Vision
Sep 2
SlideMix: Enhancing Whole Slide Image Analysis via Multimodal Shuffling
arXiv:2609.00396v1 Announce Type: new Abstract: Histopathological whole slide images (WSIs) are central to cancer diagnosis, but their gigapixel scale, tissue heterogeneity, weak slide-level supervis...
arXiv Machine Learning
Sep 3
Morphology signal in whole slide image foundation models can automatically triage slides
The paper introduces a pipeline that uses publicly available whole slide image foundation models (FMs) to automatically triage slides by ranking them based on zero‑shot classification predictions. This approach accurately identifies slides containing the most tumor, achieving top‑2 ranking for patients with up to 43 slides across multiple datasets. The study also proposes a ranked evaluation framework to benchmark FM performance in slide triage.
arXiv Computer Vision
3d ago
Beyond Sparse Captions: Aligning Slide-Level Text and Patch-Level Vision in Pathology
The paper introduces Locked Image Multiple Instance PreTraining (LIMIT), a method that aligns slide‑level pathology reports with patch‑level visual features by freezing a vision encoder and fine‑tuning a text encoder. LIMIT uses report embeddings as cross‑attention queries over bags of patch features, optimizing slide representations via InfoNCE. Applying LIMIT, the authors create CONCH‑Z, which achieves state‑of‑the‑art zero‑shot performance on 22 pathology tasks, outperforming vision‑language encoders trained on curated caption datasets and narrowing the gap with larger slide‑level foundation models.
arXiv Machine Learning
4d ago
ProtoPur: Prototype-Purity Pseudo-Labeling for Weakly Supervised Instance Learning in Pathology
arXiv:2610.15669v2 Announce Type: replace-cross Abstract: Weak bag-level labels are widely available in computational pathology, whereas reliable instance-level annotations for whole-slide images rem...