TRiST (Topology‑Reinforced Swin Transformer) augments hierarchical Vision Transformers with explicit topological information for medical image analysis. It computes 2D persistent homology (H0 and H1) at four Swin stages, refines persistence bands with gated residual networks, and injects learned key‑saliency scores into shifted‑window attention. The resulting Topo‑SwinV2‑B and Topo‑Swin‑UNet models outperform Swin baselines across five medical datasets.
By Pengfei Gu, Huimin Li, Guangyu Meng, Hao Zheng, Haoteng Tang, Bin Fu, Danny Z. Chen
VTRL-Med is a progressive visual‑structural learning framework that incorporates topology‑guided regularization for medical image clustering. It adapts the Segment Anything Model to preserve structural cues, generates pseudo‑labels via prototype selection and k‑NN consistency, and refines visual features while an auxiliary topology branch—built from persistent homology descriptors—provides geometric regularization. The method achieves state‑of‑the‑art clustering accuracy, improving average performance by 4.48% over prior approaches and further boosting accuracy by 1.3–4.3% with topology guidance.
By Guangyu Meng, Pengfei Gu, Peixian Liang, John P. Lalor, Erin Wolf Chambers, Danny Z. Chen
arXiv:2608.22281v1 Announce Type: cross
Abstract: Medical image segmentation requires high accuracy and robustness, yet practical commercial deployment also demands privacy preservation and computati...
By Bin Dong, Jinghong Chen
arXiv:2606. 29763v1 Announce Type: cross Abstract: Topological data analysis (TDA), particularly persistent homology (PH), captures geometric structural properties in medical images (e.
By Guangyu Meng, Pengfei Gu, Xueyang Li, Yiyu Shi, Erin Wolf Chambers, Danny Z. Chen
Medical image segmentation relies on the ability of encoder-decoder architectures to translate rich feature representations into accurate pixel-level predictions under challenging conditions such as low contrast, structural ambiguity, and scale variability. While recent advances in large-scale pretraining and transformer-based encoders have substantially improved feature extraction, segmentation accuracy remains constrained by decoder design, particularly in terms of cross-scale alignment, contextual integration, and boundary preservation.
Accurate coronary Digital Subtraction Angiography (DSA) vessel segmentation is essential for computer-aided diagnosis and treatment planning of coronary artery disease (CAD). However, thin low-contrast vessels, background interference, and severe vessel-background class imbalance make reliable segmentation of weak distal branches and vessel boundaries challenging.
Accurate medical image interpolation and anatomical structure segmentation are fundamental for computer-aided diagnosis and treatment planning. Anisotropic medical volumes with sparse through-plane sampling often suffer from structural discontinuity and boundary blur, hindering reliable clinical image analysis.
arXiv:2608. 07340v1 Announce Type: cross Abstract: Registration-based Few-shot medical image segmentation (RFMIS) aims to generate pseudo-labels for unlabeled images by warping a labeled image through registration.
By Jia Wang, Jiaming Cai, Zunying Hu, Zhanjie Wu, Jinyuan Liu, Hua Cheng, Yun Peng
Textual descriptions can reduce ambiguity in medical image segmentation by specifying the finding and location to be delineated. Existing text-guided methods mainly improve where image and language fe...
arXiv:2607. 09481v1 Announce Type: cross Abstract: Text-guided medical image segmentation leverages clinical semantics to improve lesion delineation, yet many existing models bind cross-modal fusion, supervision, and decoder design into a task-specific architecture.
By Yungeng Liu, Xuanzi Fang, Haijin Zeng, Qi Dai, Yongyong Chen
arXiv:2607.12896v3 Announce Type: replace
Abstract: Medical image segmentation foundation models are expected to generalize across diverse clinical scenarios, yet existing universal methods remain fr...
By Yunzhou Li, Jiesi Hu, Yanwu Yang, Hanyang Peng, Chenfei Ye, Jianfeng Cao, Yixuan Yuan, Ting Ma
The paper introduces FAD‑ViT, a vision transformer that decouples spatial and feature axes of global attention, making feature‑axis attention the primary operator. Experiments on 23 medical imaging tasks show that shifting global attention from spatial to feature leaves from‑scratch performance unchanged but significantly boosts transfer learning, achieving up to three times the gain with fewer parameters and lower compute. The study demonstrates that prioritizing feature‑axis attention is a simple, cost‑effective design choice for improving medical image transfer.
By Aon Safdar, Mohamed Saadeldin