arXiv Computation and Language

DischargeBench: Pre-Deployment Evaluation of LLM Discharge Educators through Persona-Grounded Patient Simulation

arXiv Computation and Language
Oct 5

Understanding Clinical Cognitive Dialogues Using Large Language Models

The paper introduces a de‑identified corpus of 33 in‑person cognitive assessment conversations, comprising 8,250 utterances annotated for three speaker roles and 56 dialogue acts. The authors benchmark large language models on fine‑grained dialogue‑act classification and next‑patient‑utterance generation, finding that instruction tuning and reasoning‑aware fine‑tuning improve performance but that models still struggle with closely related dialogue acts. The corpus and benchmark are presented as tools to measure interaction structure in cognitive assessments and to support future research on conversational markers, clinician education, and validated simulated patients.

By Vishalakshi Arumugam, Dan Schumacher, Veronica Rammouz, Erfan Nourbakhsh, Enrique Gonzalez Guerrero, Jeremy Davis, Anthony Rios
arXiv AI
Jun 17

AIPatient Arena: EHR-grounded evaluation of large language models in end-to-end clinical consultation workflows

arXiv:2606. 17474v1 Announce Type: cross Abstract: Large language models (LLMs) are increasingly considered for use in clinical consultation tasks, yet most medical evaluations remain static, single-turn, or narrowly outcome-based, limiting their ability to reflect the sequential, uncertain, and interactive nature of real-world care.

By Jiahui Niu, Huizi Yu, Wenkong Wang, Guangxin Dai, Jingxian He, Xiang Li, Zhiying Liang, Xinxin Lin, Kent CY So, Bryan YP Yan, Yun Kwok Wing, Yanqiu Xing, Xin Ma, Lizhou Fan
arXiv AI
Sep 12

Evaluating Scaffolding-Oriented Multi-Agent Large Language Model System for Clinical Interview Training

The study introduces a scaffolding-oriented multi-agent Large Language Model (LLM) AI Standardized Patient (AI-SP) platform designed to train medical students in patient interviews. In a randomized controlled trial with 100 students, the multi-agent system—comprising a patient agent, a Socratic tutor agent, and a turn-level evaluator—did not improve diagnostic accuracy but significantly enhanced overall OSCE scores, especially in communication, empathy, and history-taking. The authors also release a richly annotated dataset to support further research in AI-supported clinical reasoning training.

By Luming Yang, Haoxian Liu, Siqing Li, Rong Jia, Yue Xiao, Guanhua Chen, Li Lu
arXiv Computation and Language
Oct 9

Clinician use of language models diverges from how the models are evaluated

Large language model assistants are being deployed to clinicians, but their readiness is judged mainly by benchmark scores that are based on examination questions or curated cases. This study analyzed 127,833 queries from 6,342 healthcare professionals across 35 specialties, finding that most requests were for documentation, administration, and knowledge retrieval, with a significant portion of queries unanswerable. When compared to 58 public benchmarks, the median benchmark lacked documentation requests and only shared 31% of the real task mix, indicating that current benchmarks poorly reflect actual clinical use.

By Krithik Vishwanath, Haitong Lin, Anton Alyakin, Jin Vivian Lee, D. Brock Hewitt, Jie J. Yao, William Robert Small, Hammad A. Khan, Cordelia Orillac, Aakaash Varma, Brandon Ye, Daniel Alexander Alber, Gustavo Stolovitzky, Batia Wiesenfeld, Oded Nov, Wei Wu, Kang Zhang, Yindalon Aphinyanaphongs, Tim Requarth, Eric Karl Oermann, The International Digital Twin Consortium in Healthcare, Medicine
arXiv AI
Jul 28

OpenAIs HealthBench in Action: Evaluating an LLM-Based Medical Assistant on Realistic Clinical Queries

arXiv:2509. 02594v3 Announce Type: replace-cross Abstract: Evaluating large language models (LLMs) on their ability to generate high-quality, accurate, situationally aware answers to clinical questions requires going beyond conventional benchmarks to assess how these systems behave in complex, high-stakes clinical scenarios.

By Sandhanakrishnan Ravichandran, Shivesh Kumar, Rogerio Corga Da Silva, Miguel Romano, Reinhard Berkels, Michiel van der Heijden, Olivier Fail, Valentine Emmanuel Gnanapragasam
arXiv Computation and Language
6d ago

MindEval2: Clinically Grounded Patients and Rubrics for Evaluating Language Models in Mental Health Support

MindEval2 is a new evaluation framework for AI chatbots in mental health support, comprising Mental Health Quality Rubrics (MHQR) and the MindSim patient simulation harness. MHQR, developed with PhD-level psychologists, provides explicit, actionable criteria for assessing response quality, while MindSim offers realistic, longitudinal patient interactions with a memory component. The study evaluated 18 models, finding that although surface-level quality has improved, guidance calibration remains the main failure across all models.

By John Mendon\c{c}a, Daniel Tschernutter, Jos\'e Pombal, Areti Vassilopoulos, Catarina Botelho, Ignacio Sarasua, Maya D'Eon, Nuno Guerreiro, Ricardo Rei
arXiv Computation and Language
Oct 7

Evaluating Large Language Model Raters for German Open-Response Clinical Questions: A Physician-Annotated Benchmark Study of Agreement, Evaluator Bias, and Abstention

The study introduces MedQADE, a German open‑response clinical benchmark with 3,800 question‑answer pairs and physician reference annotations. It evaluates large language models (LLMs) as judges, finding that while some LLMs (e.g., Gemini 3 Flash) achieve physician‑level agreement on correctness, they exhibit self‑bias and low abstention rates. Physicians showed moderate agreement on correctness but limited agreement on difficulty, and their abstention increased with perceived difficulty.

By William Philipp, Finn Fassbender, Daniel Fister, Thorsten Langer, Martje G. Pauly, Rebecca Herzog, Markus A. Hobert, Theresa Paulus, Alexander Baumann, Chi Wang Ip, Lukas L. Goede, Johanna Reimer, Sebastian L\"ons, Ronald B\"ock, Sebastian Fudickar
arXiv Computation and Language
Oct 12

DistressBench: Evaluating Multi-Dimensional Crisis Support in Large Language Models

The paper introduces DistressBench, a benchmark comprising 718 English clinician-authored conversations covering 23 self-harm subcategories, each evaluated against a weighted rubric across seven crisis-support dimensions. Models are scored by the fraction of criteria they satisfy, revealing that the best models meet 88.4% of weighted criteria while clinicians achieve 98.7%. The study highlights gaps in crisis response, notably that 35.3% of conversations where crisis is recognized fail to route users to human help, underscoring the need to evaluate models on supportive care rather than mere refusal.

By Drew Rein, Patrick Oathout, Vishal Kumar, Udari Madhushani Sehwag
arXiv Computation and Language
Aug 27

EduDial: Constructing a Large-scale Multi-turn Teacher-Student Dialogue Corpus

EduDial is a large-scale multi-turn teacher‑student dialogue corpus covering 345 core knowledge points and 34,250 dialogue sessions, designed around Bloom’s taxonomy and ten questioning strategies such as situational, ZPD, and metacognitive questioning. The dataset includes differentiated teaching strategies for students at varying cognitive levels to provide targeted guidance. Using EduDial, the authors trained EduDial‑LLM 32B and introduced an 11‑dimensional evaluation framework that measures teaching quality and content quality, showing that most mainstream LLMs struggle with student‑centered teaching while EduDial‑LLM outperforms all baselines across all metrics.

By Shouang Wei, Min Zhang, Xin Lin, Bo Jiang, Zhongxiang Dai, Kun Kuang