arXiv AI

OPERA: Offline Policy-guided Expert Routing and Adaptation for Universal Biomedical Image Analysis

arXiv:2607. 25108v1 Announce Type: cross Abstract: Biomedical image analysis spans diverse modalities and tasks, yet real-world deployment is hindered by severe distribution shifts across scanners, protocols, and patient populations.

arXiv Machine Learning
Aug 3

MoPET: Parameter-Efficient Mixture-of-Experts for Unified Medical Image Classification

arXiv:2607. 29462v1 Announce Type: cross Abstract: Adapting deep learning models to profound clinical heterogeneity typically relies on parameter-efficient fine-tuning (PEFT) to avoid the severe overfitting associated with full end-to-end network updates.

By Sebastian Doerrich, Daniel W\"urtinger, Francesco Di Salvo, Shyam Nandan Rai, Christian Ledig
arXiv AI
Jun 11

Human-Guided Agentic AI for Multimodal Clinical Prediction: Lessons from the AgentDS Healthcare Benchmark

arXiv:2602. 19502v2 Announce Type: replace Abstract: Agentic AI systems are increasingly capable of autonomous data science workflows, yet clinical prediction tasks demand domain expertise that purely automated approaches struggle to provide.

By Lalitha Pranathi Pulavarthy, Raajitha Muthyala, Aravind V Kuruvikkattil, Zhenan Yin, Rashmita Kudamala, Saptarshi Purkayastha
arXiv Machine Learning
Aug 17

MedMix: Specialization-Consistent Federated Sparse MoEs under Modality Heterogeneity

arXiv:2608. 13911v1 Announce Type: new Abstract: Federated multimodal medical AI faces modality heterogeneity at both the client and sample levels: clients may systematically lack access to specific modality types, while individual records within the same client may contain different partial modality subsets.

By Adiba Orzikulova, Dong Min Kim, Jaehong Yoon, Sung-Ju Lee
arXiv Computer Vision
Aug 25

Can Coding Agents Build Robust Baselines? A Skill-Based Approach for Automating the Medical Imaging Model-Development Pipeline

The paper introduces an agentic AI Scientist workflow that automates the entire baseline development process for medical imaging by combining literature-guided reasoning, automated code generation, and hypothesis-driven experimentation. Evaluated on four public benchmarks covering segmentation, classification, and detection, the pipeline consistently improves validation performance, achieving competitive leaderboard results such as 6th place on both PUMA tracks and 31st on MILK10k. The approach also shows strong domain generalization on MIDOG25 across scanners, tumor types, and species, demonstrating that a skill-based, literature-guided agentic workflow can reduce engineering effort without task-specific redesign.

By Eugenia Moris, Jos\'e Ignacio Orlando
arXiv AI
Aug 20

A Few Cases Are All You Need: An Empirical Study of Annotation-Efficient LoRA Fine-Tuning of MedSAM3

The study investigates how few expert-annotated cases are needed to fine‑tune MedSAM3 for abdominal organ segmentation using Low‑Rank Adaptation (LoRA). With only 10 annotated CT or MRI cases, the LoRA‑adapted models achieve performance comparable to specialist systems that require orders of magnitude more data, including reliable gallbladder segmentation and near‑state‑of‑the‑art results for liver, kidneys, and spleen. The approach also generalizes to cardiac segmentation on the Whole Heart dataset, and training takes only 3–5 hours per organ on a single GPU, roughly twice as fast as nnU-Net.

By Sachin Dudda Nagaraju, Bendik Skarre Abrahamsen, Ashkan Moradi, Mattijs Elschot
arXiv AI
Jun 24

BioMedArena: An Open-source Toolkit for Building and Evaluating Biomedical Deep Research Agents

arXiv:2605. 06177v2 Announce Type: replace Abstract: Reproducing and comparing deep research agents today is hard: the same backbone evaluated on the same benchmark can report different accuracies across papers because the harness and tool registry differ, and integrating a new model into a comparable evaluation surface costs weeks of model-specific engineering.

By Jinge Wu, Hongjian Zhou, Mingde Zeng, Jiayuan Zhu, Junde Wu, Jiazhen Pan, Ayush Noori, Sean Wu, Honghan Wu, Fenglin Liu, David A. Clifton