MM‑Net is a multimodal, multi‑task neural network designed to simultaneously stage sleep and detect respiratory events in patients after ischemic stroke. It fuses sleep‑adapted EEG‑EOG embeddings with engineered neural descriptors and cardiorespiratory features using cross‑attention and shared temporal modeling, and employs cross‑fitting and ridge‑based embedding alignment to maintain representation consistency across patients. In a patient‑independent evaluation on the iSLEEPS dataset, MM‑Net achieved 76.3 % sleep‑stage accuracy (κ = 0.656) and a 0.825 AUC for respiratory‑event detection, outperforming baseline models; it also performed strongly on Sleep‑EDF and ISRUC‑I datasets and retained high respiratory AUCs when applied to unseen cohorts without retraining.
arXiv:2512. 14461v2 Announce Type: replace Abstract: Sleep is essential for health, yet studying its dynamics requires manual sleep staging, a labor-intensive step in research and clinical care.
arXiv:2607. 07720v1 Announce Type: cross Abstract: Sleep physiology arises from the coordinated dynamics of the central nervous system (CNS) and autonomic nervous system (ANS), as reflected by multimodal polysomnography signals including EEG, EOG, EMG, ECG, and respiration.
arXiv:2607. 07720v2 Announce Type: replace-cross Abstract: Sleep physiology arises from the coordinated dynamics of the central nervous system (CNS) and autonomic nervous system (ANS), as reflected by multimodal polysomnography signals including EEG, EOG, EMG, ECG, and respiration.
SleepFM-2 is a foundation model trained on 282,511 polysomnography recordings, covering over two million hours of multimodal sleep physiology. It outperforms its predecessor in disease prediction, sleep scoring, and event detection, and its representation improves performance across diverse tasks—including wearable sensing, subjective sleep reports, and transfer to other EEG modalities. When combined with age, sex, and BMI, the model meets stringent discrimination criteria for 215 EHR phenotypes, adding reproducible information beyond demographics for 155 of them.
arXiv:2610.15351v1 Announce Type: cross Abstract: Amyotrophic lateral sclerosis (ALS) diagnosis remains challenging due to heterogeneous symptoms and reliance on clinical assessment, underscoring the...
Hypnos is a multi‑modal sleep foundation model that learns generalisable representations of physiological signals by predicting the next token across eight sensing modalities (EEG, ECG, respiratory, etc.) using an auto‑regressive RQ‑Transformer. Trained on over 20,000 overnight polysomnography recordings, it outperforms existing foundation models on most benchmarks, matching strong supervised baselines for sleep‑stage classification while requiring 100× less labelled data. Additionally, Hypnos generalises beyond sleep, surpassing a dedicated ECG model in atrial fibrillation detection.
arXiv:2606. 09605v1 Announce Type: new Abstract: Foundation models offer a promising route to compress multi-modal physiological signals into compact representations of human health, with broad applications across sleep medicine, cardiology, neurology and other healthcare domains.
arXiv:2607. 23554v1 Announce Type: cross Abstract: In this paper, we propose the MAEConformer, a novel self-supervised learning framework that combines the Conformer architecture with the Masked Autoencoder (MAE) paradigm for large-scale representation learning from unlabelled electroencephalography (EEG) and heart rate variability (HRV) signals.
Brain4FMs is a unified benchmark for evaluating brain foundation models (BFMs) on both scalp EEG and intracranial EEG (iEEG). It incorporates 17 representative models and 21 public datasets spanning clinical diagnosis, sleep staging, communication, and affective computing, and offers dataset-aware preprocessing, cross‑subject evaluation, and standardized downstream workflows. The benchmark highlights that no single BFM consistently outperforms others across all tasks, modalities, and adaptation protocols, prompting further exploratory analyses of model‑specific spatial, spectral, and discrete representations.
The study compares six state‑of‑the‑art sleep‑staging foundation models on the MESA polysomnography dataset under three signal conditions: EEG only, ECG only, and EEG+ECG. Results show that EEG alone yields the highest accuracy (BIOT macro‑F1 = 0.7237), while switching to ECG alone incurs a consistent accuracy loss of about 0.35 macro‑F1 and reduces data rate to one‑third. Adding ECG to EEG offers little benefit for most models, indicating that EEG carries most of the sleep‑staging signal and that wearable‑compatible ECG alone is a viable but less accurate alternative.
arXiv:2506.20354v3 Announce Type: replace-cross Abstract: Learning from multi-variate time-series with heterogeneous channel configurations remains a fundamental challenge for deep neural networks, p...
arXiv:2602. 07628v2 Announce Type: replace Abstract: While the shift toward unified foundation models has revolutionized many deep learning domains, sleep medicine remains largely restricted to task-specific models that focus on localized micro-structure features.